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There is a significant correlation between mortality in the critically ill patients in the intensive care unit and increased serum concentration of S100B and NSE (zeige ENO2 Antikörper).
Our findings showed that both S100beta and NSE (zeige ENO2 Antikörper) levels similarly increased during CPB (zeige CPB1 Antikörper) and immediately after CPB (zeige CPB1 Antikörper) during sevoflurane and propofol based anesthesia.
This study demonstrated that S100A12 (zeige S100A12 Antikörper) mRNA levels were significantly decreased in the new cases of untreated MS patients in comparison to healthy controls.
Increased serum levels of S100B protein (and NSE (zeige ENO2 Antikörper)) were observed postoperatively in patients with postoperative cognitive dysfunction.
high S100B expression in Multiple Sclerosis (MS) patient samples suggests its usefulness as a diagnostic biomarker for MS.
the underlying mechanism of S100B-mediated effects on cancer stem-like cell stemness was not dependent on its binding with a receptor for advanced glycation end products (RAGE (zeige AGER Antikörper)), but might be through intracellular regulation, through the inhibition of p53 (zeige TP53 Antikörper) expression and phosphorylation.
Data show that a high serum S100beta protein level, hypertension, and high low density lipoprotein-cholesterol (LDL-C) level were the independent risk factors for cerebral small vessel disease (SVD (zeige KCNJ13 Antikörper)).
the serum concentrations of S100B are increased in bipolar disorder patients.
Levels of NSE and S100B are still elevated 1 year postpartum in women who have had preeclampsia in contrast to women with previous normal pregnancies.
In vitro experiments using repeated freeze-thaw procedures showed an intracellular up-regulation of S100B in normal and vitiligo (zeige MITF Antikörper) melanocytes before an extensive release in the environment.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21\; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
S-100 calcium-binding protein, beta chain
, S-100 protein subunit beta
, S100 calcium-binding protein, beta (neural)
, protein S100-B