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Human Polyclonal GLIPR1 Primary Antibody für ELISA - ABIN449364
Ren, Li, Yang, Timme, Goltsov, Ren, Ji, Addai, Luo, Ittmann, Thompson: RTVP-1, a tumor suppressor inactivated by methylation in prostate cancer. in Cancer research 2004
High GLIPR1 expression is associated with cisplatin resistance in lung cancer.
The present study identified GLIPR1 and miR-16 (zeige GDE1 Antikörper) as key components for regulating the proliferation, migration, invasion and cancer-initiating cells in osteosarcoma
This study reveals a novel pathway that PRMT5 (zeige PRMT5 Antikörper)/WDR77 (zeige WDR77 Antikörper) regulates GLIPR1 expression to control lung cancer cell growth.
Overexpression of RTVP-1 in human neural stem cells induced mesenchymal differentiation, whereas silencing of RTVP-1 in glioma stem cells (GSCs) decreased the mesenchymal transformation and stemness of these cells.
RTVP-1 regulates glioma cell spreading, migration and invasion and that these effects are mediated via interaction with N-WASP and by interfering with the inhibitory effect of hnRNPK (zeige HNRNPK Antikörper) on the function of this protein.
Data indicate that combining adenoviral vector-mediated GLIPR1 gene therap (AdGLIPR1) with radiotherapy may achieve additive or synergistic tumor control in selected prostate and bladder tumors.
Based on the observed overexpression in AML (zeige RUNX1 Antikörper) samples, GliPR1 should be further explored as a potential target for AML (zeige RUNX1 Antikörper)
miR (zeige MLXIP Antikörper)-137 inhibits Glioblastom stem cell self-renewal and promotes their differentiation by targeting RTVP-1 which down-regulates CXCR4 (zeige CXCR4 Antikörper).
GLIPR1 interacts with Hsc70 (zeige HSPA8 Antikörper), and GLIPR1 overexpression or Hsc70 (zeige HSPA8 Antikörper) knockdown leads to transcriptional suppression of AURKA (zeige AURKA Antikörper) and TPX2 (zeige TPX2 Antikörper).
GLIPR1 core structure has a conserved central cavity via which CAP proteins are likely to bind to shared ligands.
The genetic variation is a key determining factor for the alternative splicing events in the Gli1 (zeige GLI1 Antikörper) 5' UTRs, which have functional implications on translational efficiency.
Identification of a novel mouse gene, mRTVP-1, as a p53 (zeige TP53 Antikörper) target gene. The mRTVP-1 protein has 255 amino acids and differs from the human RTVP-1 protein by two short in-frame deletions of two and nine amino acids. (mRTVP-1)
This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized.
GLI pathogenesis-related 1 (glioma)
, glioma pathogenesis-related protein 1
, gliPR 1
, protein RTVP-1
, related to testis-specific, vespid, and pathogenesis proteins 1
, testes-specific vespid and pathogenesis protein 1
, related to testes-specific, vespid, and pathogenesis proteins
, GLI pathogenesis-related 1
, glioma pathogenesis-related protein