anti-Human FDFT1 Antikörper für Enzyme Immunoassay

Recommended FDFT1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) Antikörper
  • FDFT1
  • DKFZp459C1712
  • SQS
  • SS
  • DGPT
  • ERG9
  • fdft1
  • farnesyl-diphosphate farnesyltransferase 1
  • squalene synthase
  • farnesyl diphosphate farnesyl transferase 1
  • FDFT1
  • fdft1
  • LOC100560926
  • Fdft1
Epitop
N-Term
12
11
11
10
10
9
7
7
7
5
5
5
4
4
2
1
1
Reaktivität
Human, Maus
108
32
16
4
3
2
2
2
2
1
1
1
Wirt
Kaninchen
103
17
Klonalität
Polyklonal
Konjugat
Dieser FDFT1 Antikörper ist unkonjugiert
11
11
7
6
6
6
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
116
65
60
14
14
9
7
6
4
2
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN357711
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
7 ABIN357712 EIA IHC (p) WB Rabbit Ig Fraction Middle Region Anmelden zum Anzeigen Polyclonal 2

General

Antigen Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) Antikörper
Epitop N-Term
(12), (11), (11), (10), (10), (9), (7), (7), (7), (5), (5), (5), (4), (4), (2), (1), (1)
Reaktivität Human, Maus
(108), (32), (16), (4), (3), (2), (2), (2), (2), (1), (1), (1)
Wirt Kaninchen
(103), (17)
Klonalität
Polyklonal
Konjugat Dieser FDFT1 Antikörper ist unkonjugiert
(11), (11), (7), (6), (6), (6)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(116), (65), (60), (14), (14), (9), (7), (6), (4), (2), (1)
Pubmed 6 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-FDFT1 Antikörper

Target Details FDFT1 Anwendungsinformationen Handhabung Referenzen für anti-FDFT1 Antikörper (ABIN357711) Bilder
Spezifität This antibody detects FDFT1 (N-term).
Reinigung Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human FDFT1.
Isotyp Ig Fraction
Plasmids, Primers & others

Target Details FDFT1

Produktdetails anti-FDFT1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-FDFT1 Antikörper (ABIN357711) Bilder zurück nach oben
Antigen
Andere Bezeichnung Squalene Synthetase (FDFT1 Antibody Abstract)
Hintergrund FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.Synonyms: FDFT1, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, SQS, SS
Molekulargewicht 48115 Da
Gen-ID 2222, 5874
UniProt P37268
Pathways Regulation of Lipid Metabolism by PPARalpha

Anwendungsinformationen

Produktdetails anti-FDFT1 Antikörper Target Details FDFT1 Handhabung Referenzen für anti-FDFT1 Antikörper (ABIN357711) Bilder zurück nach oben
Applikations-hinweise ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-FDFT1 Antikörper Target Details FDFT1 Anwendungsinformationen Referenzen für anti-FDFT1 Antikörper (ABIN357711) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-FDFT1 Antikörper (ABIN357711)

Produktdetails anti-FDFT1 Antikörper Target Details FDFT1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002

Soltis, McMahon, Caplan, Dudas, Chamberlin, Vattay, Dottavio, Rucker, Engstrom, Cornell-Kennon: "Expression, purification, and characterization of the human squalene synthase: use of yeast and baculoviral systems." in: Archives of biochemistry and biophysics, Vol. 316, Issue 2, pp. 713-23, 1995

Summers, Karst, Charles: "Cloning, expression and characterisation of the cDNA encoding human hepatic squalene synthase, and its relationship to phytoene synthase." in: Gene, Vol. 136, Issue 1-2Che, pp. 185-92, 1994

Jiang, McKenzie, Conrad, Shechter: "Transcriptional regulation by lovastatin and 25-hydroxycholesterol in HepG2 cells and molecular cloning and expression of the cDNA for the human hepatic squalene synthase." in: The Journal of biological chemistry, Vol. 268, Issue 17, pp. 12818-24, 1993

Robinson, Tsay, Kienzle, Smith-Monroy, Bishop: "Conservation between human and fungal squalene synthetases: similarities in structure, function, and regulation." in: Molecular and cellular biology, Vol. 13, Issue 5, pp. 2706-17, 1993

Zinkl, Roberts, Shea, Lasmanis: "Toxicity of acephate and methamidophos to dark-eyed juncos." in: Archives of environmental contamination and toxicology, Vol. 10, Issue 2, pp. 185-92, 1981

Bilder

Produktdetails anti-FDFT1 Antikörper Target Details FDFT1 Anwendungsinformationen Handhabung Referenzen für anti-FDFT1 Antikörper (ABIN357711) zurück nach oben
Bilder des Herstellers
 image for anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (N-Term) antibody (ABIN357711) anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (N-Term) antibody
 image for anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (N-Term) antibody (ABIN357711) anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (N-Term) antibody (Image 2)