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Human Polyclonal XCL1 Primary Antibody für ELISA, WB - ABIN562827
Venetz, Ponzoni, Schiraldi, Ferreri, Bertoni, Doglioni, Uguccioni: Perivascular expression of CXCL9 and CXCL12 in primary central nervous system lymphoma: T-cell infiltration and positioning of malignant B cells. in International journal of cancer. Journal international du cancer 2010
Human Polyclonal XCL1 Primary Antibody für Func, IHC (p) - ABIN2475402
Kennedy, Kelner, Kleyensteuber, Schall, Weiss, Yssel, Schneider, Cocks, Bacon, Zlotnik: Molecular cloning and functional characterization of human lymphotactin. in Journal of immunology (Baltimore, Md. : 1950) 1995
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Human Polyclonal XCL1 Primary Antibody für ELISA - ABIN4219731
Tuinstra, Peterson, Kutlesa, Elgin, Kron, Volkman: Interconversion between two unrelated protein folds in the lymphotactin native state. in Proceedings of the National Academy of Sciences of the United States of America 2008
study provides in vitro and in vivo evidence that the interaction between XCL1 and alpha9 integrin has an important role for autoimmune diseases
The interaction between XCL1 and XCR1 (zeige XCR1 Antikörper) plays a crucial role in the classical immunology response.
Data show that mice lacking either XCL1 or XCR1 (zeige XCR1 Antikörper) exhibit similar specific defects in intestinal T cell populations as XCR1 (zeige XCR1 Antikörper)-dendritic cells (DC)-deficient mice. Therefore it is possible that the XCR1 (zeige XCR1 Antikörper)-XCL1 axis itself is directly involved in intestinal T cell homeostasis, via a mechanism that might either involve interaction with XCR1 (zeige XCR1 Antikörper)+ DCs or be independent of this pathway.
T inflammatory memory CD8 (zeige CD8A Antikörper) T cells participate to antiviral response and generate secondary memory cells with an advantage in XCL1 production
XCL1-mediated accumulation of dendritic cells in the thymic medulla contributes to naturally occurring regulatory T cell development and is regulated by Aire (zeige AIRE Antikörper).
Data report the identification of a new stable molecular assembly formed between the ATAC and Mediator complexes in mouse embryonic stem cells.
The expression patterns of XCR1 (zeige XCR1 Antikörper) and XCL1 were conserved in human and mice blood cells, including certain dendritic cell subsets.
MIP-1alpha (zeige CCL3 Antikörper), MIP-1beta (zeige CCL4 Antikörper), RANTES (zeige CCL5 Antikörper), and ATAC/lymphotactin function together with IFN-gamma (zeige IFNG Antikörper) as type 1 cytokines.
Adenovirus-mediated intratumoral Lptn gene transfer potentiates the antibody-targeted superantigen therapy of experimental melanoma.
In a brain-targeted HIV-1 Tat transgenic model, Tat exp (zeige TAT Antikörper)ression up-regulates XCL1 production not only in Tat-expressing murine astrocytes, but also in monocytes and macrophages/microglia.
higher serum XCL1 levels at diagnosis and their progressive decline throughout chemotherapy could be correlated with higher survival.
This study defines a Glycosaminoglycan binding surface on XCL1 dimer that includes residues that are important for HIV-1 inhibition.
Electrostatics and Hydrophobic Effects in the Metamorphic Protein Human Lymphotactin
XCL1 acts via direct interaction with the external viral envelope glycoprotein (zeige ERVW-1 Antikörper), gp120 (zeige ITIH4 Antikörper), to block HIV-1 infection
analysis of XCL1 and XCL2 (zeige XCL2 Antikörper), members of the C-chemokine (zeige CCL1 Antikörper) subfamily, in the immune system
identified 13 ADCC-activated genes. Six gene expression assays including 8 of the 13 genes (CCL3 (zeige CCL3 Antikörper), CCL4/CCL4L1 (zeige CCL4 Antikörper)/CCL4L2, CD160 (zeige CD160 Antikörper), IFNG (zeige IFNG Antikörper), NR4A3 (zeige NR4A3 Antikörper) and XCL1/XCL2 (zeige XCL2 Antikörper)) were analyzed in 127 kidney biopsies
XCL1 displays antimicrobial activity against E. coli and S. aureus.
XCL1-mediated inhibition is associated with direct interaction of the chemokine (zeige CCL1 Antikörper) with the HIV-1 envelope.
In native annulus fibrosus tissue homeostasis and repair, CXCR3 (zeige CXCR3 Antikörper) is evident, whereas XCL1 could not be detected.
The distribution characters of cattle XCR1 (zeige XCR1 Antikörper) and XCL1 suggested a vital role in regulation of acquired immune responses and indicated a potential for a DC targeted veterinary vaccine in cattle using XCL1 fused antigens.
This gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.
chemokine (C motif) ligand 1
, c motif chemokine 1
, cytokine SCM-1
, small inducible cytokine subfamily C, member 1 (lymphotactin)
, small-inducible cytokine C1
, XC chemokine ligand 1
, single cysteine motif 1a