anti-Schwein SH2 Domain Containing 1A Antikörper für Western Blotting

Recommended SH2 Domain Containing 1A Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
SH2 Domain Containing 1A (SH2D1A) Antikörper
  • DSHP
  • EBVS
  • IMD5
  • LYP
  • MTCP1
  • SAP
  • SAP/SH2D1A
  • XLP
  • XLPD
  • RGD1562408
  • Gm686
  • SH2D1A
  • SH2 domain containing 1A
  • SH2D1A
  • Sh2d1a
Epitop
C-Term
18
17
14
9
5
4
4
4
3
3
2
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Pferd, Human, Schwein, Ratte (Rattus)
122
42
35
7
6
4
2
1
1
1
1
Wirt
Kaninchen
84
35
7
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
7
7
6
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
104
61
13
13
7
4
2
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2788421
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
7.8026066 ABIN2559908 ELISA WB Goat IgG Internal Region Anmelden zum Anzeigen Polyclonal 0
7 ABIN297646 ELISA WB Goat AA 99-112 Anmelden zum Anzeigen Polyclonal 0
4.8026066 ABIN2707041 WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
4.8026066 ABIN2774285 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN2744334 WB Rabbit Internal Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN2972147 WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0

General

Antigen SH2 Domain Containing 1A (SH2D1A) Antikörper
Epitop C-Term
(18), (17), (14), (9), (5), (4), (4), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Pferd, Human, Schwein, Ratte (Rattus)
(122), (42), (35), (7), (6), (4), (2), (1), (1), (1), (1)
Wirt Kaninchen
(84), (35), (7), (1)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(7), (7), (6), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(104), (61), (13), (13), (7), (4), (2), (2), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN983683.
Sequenz YFRKIKNLIS AFQKPDQGIV IPLQYPVEKK SSARSTQGTT GIREDPDVCL
Homologie Cow: 86%, Horse: 92%, Human: 100%, Pig: 100%, Rat: 93%
Produktmerkmale This is a rabbit polyclonal antibody against SH2D1A. It was validated on Western Blot.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human SH2D1A

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung SH2D1A (SH2D1A Antibody Abstract)
Hintergrund SH2D1A is a protein that plays a major role in the bidirectional stimulation of T and B cells. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in SH2D1A gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma.
Alias Symbols: DSHP, EBVS, FLJ18687, FLJ92177, IMD5, LYP, MTCP1, SAP, XLP, XLPD, SAP/SH2D1A
Protein Interaction Partner: LHX4, TNK2, UBC, LYN, MAPK11, MAPK1, ERBB3, EGFR, MAPK14, CD244, ELAVL1, SLAMF7, SLAMF6, ARHGEF7, CD84, SLAMF1, DOK1, FYB, LY9, ARHGEF6, LCK, FYN, GRB2,
Protein Size: 128
Molekulargewicht 14 kDa
Gen-ID 4068
NCBI Accession NM_002351, NP_002342
UniProt O60880
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 128 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-SH2 Domain Containing 1A (SH2D1A) (C-Term) antibody (ABIN2788421) WB Suggested Anti-SH2D1A Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive...
Western Blotting (WB) image for anti-SH2 Domain Containing 1A (SH2D1A) (C-Term) antibody (ABIN2788421) WB Suggested Anti-SH2D1A Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 Posi...