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General |
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Antigen | Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Antikörper |
Epitop | N-Term Alternativen |
Reaktivität | Hund, Human, Maus, Ratte (Rattus) Alternativen |
Wirt | Ziege Alternativen |
Klonalität | |
Konjugat | Dieser P2RX7 Antikörper ist unkonjugiert Alternativen |
Applikation |
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternativen
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Hersteller | Anmelden zum Anzeigen |
Produktdetails anti-P2RX7 AntikörperTarget Details P2RX7 Anwendungsinformationen Handhabung Bilder |
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Sequenz | YETNKVTRIQ SMNY-C |
Spezifität | This antibody recognizes P2X7 receptor. |
Kreuzreaktivität (Details) |
Species reactivity (expected):Mouse, Rat, Canine. Species reactivity (tested):Human. |
Reinigung | Affinity Chromatography |
Immunogen | Peptide with sequence from the N-Terminus of the protein sequence (NP_002553.2). Genename: P2RX7 |
Target Details P2RX7Produktdetails anti-P2RX7 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben |
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Antigen | |
Andere Bezeichnung | P2RX7 / P2X7 (P2RX7 Antibody Abstract) |
Hintergrund | The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.Synonyms: ATP receptor, P2X purinoceptor 7, P2Z receptor, Purinergic receptor |
Molekulargewicht | 68.6kDa (NP_002553.2). |
Gen-ID | 5027 |
NCBI Accession | NP_002553 |
UniProt | Q99572 |
Pathways | Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis |
AnwendungsinformationenProduktdetails anti-P2RX7 Antikörper Target Details P2RX7 Handhabung Bilder zurück nach oben |
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Applikationshinweise |
Peptide ELISA: 1/16000. Western blot: 1 - 3 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails anti-P2RX7 Antikörper Target Details P2RX7 Anwendungsinformationen Bilder zurück nach oben |
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Konzentration | 0.5 mg/mL |
Buffer | Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer |
Konservierungsmittel | Sodium azide |
Vorsichtsmaßnahmen | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handhabung | Avoid repeated freezing and thawing. |
Lagerung | 4 °C/-20 °C |
Informationen zur Lagerung | Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. |