anti-Pferd P2RX7 Antikörper für Western Blotting

Recommended P2RX7 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Antikörper
  • p2xr7
  • P2RX7
  • P2X7
  • AI467586
  • P2X(7)
  • P2X7R
  • p2x7
  • purinergic receptor P2X 7
  • purinergic receptor P2X, ligand-gated ion channel, 7
  • P2X purinoceptor 7
  • P2RX7
  • p2rx7
  • LOC100458463
  • P2rx7
Epitop
Middle Region
21
19
14
4
4
3
3
3
3
2
2
2
2
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
95
77
37
4
3
3
3
2
2
2
2
Wirt
Kaninchen
77
25
19
4
Klonalität
Polyklonal
Konjugat
Dieser P2RX7 Antikörper ist unkonjugiert
8
4
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
79
52
45
28
23
21
19
13
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2776151
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.2802403 ABIN2776334 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 0
3.2802403 ABIN2776335 IHC WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 2
1 ABIN468079 WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0

General

Antigen Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Antikörper
Epitop Middle Region
(21), (19), (14), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
(95), (77), (37), (4), (3), (3), (3), (2), (2), (2), (2)
Wirt Kaninchen
(77), (25), (19), (4)
Klonalität
Polyklonal
Konjugat Dieser P2RX7 Antikörper ist unkonjugiert
(8), (4), (4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(79), (52), (45), (28), (23), (21), (19), (13), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-P2RX7 Antikörper

Target Details P2RX7 Anwendungsinformationen Handhabung Referenzen für anti-P2RX7 Antikörper (ABIN2776151) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN981273.
Sequenz LRHCAYRCYA TWRFGSQDMA DFANLPSCCR WRIRKEFPKS EGQYSGFKSP
Homologie Cow: 100%, Dog: 93%, Guinea Pig: 83%, Horse: 86%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 93%, Rat: 85%
Produktmerkmale This is a rabbit polyclonal antibody against P2RX7. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human P2RX7

Target Details P2RX7

Produktdetails anti-P2RX7 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-P2RX7 Antikörper (ABIN2776151) Bilder zurück nach oben
Antigen
Andere Bezeichnung P2RX7 (P2RX7 Antibody Abstract)
Hintergrund The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay (NMD) criteria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC20089, P2X7
Protein Interaction Partner: KRTAP10-8, KRT31, TM9SF1, CASK, EFNB3, EMP3, PANX1, SVIL, ACTB,
Protein Size: 595
Molekulargewicht 68 kDa
Gen-ID 5027
NCBI Accession NM_002562, NP_002553
UniProt Q99572
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis

Anwendungsinformationen

Produktdetails anti-P2RX7 Antikörper Target Details P2RX7 Handhabung Referenzen für anti-P2RX7 Antikörper (ABIN2776151) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 595 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-P2RX7 Antikörper Target Details P2RX7 Anwendungsinformationen Referenzen für anti-P2RX7 Antikörper (ABIN2776151) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-P2RX7 Antikörper (ABIN2776151)

Produktdetails anti-P2RX7 Antikörper Target Details P2RX7 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Al-Shukaili, Al-Kaabi, Hassan: "A comparative study of interleukin-1beta production and p2x7 expression after ATP stimulation by peripheral blood mononuclear cells isolated from rheumatoid arthritis patients and normal healthy controls." in: Inflammation, Vol. 31, Issue 2, pp. 84-90, 2008

Bilder

Produktdetails anti-P2RX7 Antikörper Target Details P2RX7 Anwendungsinformationen Handhabung Referenzen für anti-P2RX7 Antikörper (ABIN2776151) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (Middle Region) antibody (ABIN2776151) WB Suggested Anti-P2RX7 Antibody Positive Control: Lane 1: 50ug mock transfected HEK...
Western Blotting (WB) image for anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (Middle Region) antibody (ABIN2776151) WB Suggested Anti-P2RX7 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive...