anti-Human CD24 Antikörper für Immunohistochemistry (Frozen Sections)

Recommended CD24 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
CD24 Molecule (CD24) Antikörper
  • CD24A
  • Cd24a
  • Cd24
  • HSA
  • Ly-52
  • nectadrin
  • CD24 molecule
  • CD24a antigen
  • CD24
  • Cd24
  • Cd24a
Reaktivität
Human
272
193
25
4
1
Wirt
Maus
212
168
73
1
Klonalität
Monoklonal
Konjugat
Dieser CD24 Antikörper ist unkonjugiert
54
50
34
26
13
11
7
7
6
6
5
5
5
5
4
4
4
4
4
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
Applikation
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
359
98
91
77
54
47
30
26
20
18
8
6
5
5
4
2
1
1
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Produktnummer ABIN238502
$ 308.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN262828 ICC FACS IHC (fro) IF IHC Mouse IgG2a kappa Anmelden zum Anzeigen ML5 0
1 ABIN255864 FACS IHC (fro) IHC Mouse IgG1 Anmelden zum Anzeigen SN3 0
1 ABIN2479403 IHC (fro) FACS Mouse IgG1 Anmelden zum Anzeigen SN3 4
1 ABIN781712 IHC (fro) FACS Mouse IgG1 Anmelden zum Anzeigen 32D12 0
1 ABIN384546 FACS IHC (fro) WB Mouse IgG1, kappa Anmelden zum Anzeigen SN3 0
1 ABIN2479407 IHC (fro) FACS Mouse IgG1 Anmelden zum Anzeigen SN3 4
1 ABIN118567 FACS IHC (fro) Mouse IgG1 Anmelden zum Anzeigen SN3 2
1 ABIN111241 FACS IHC (fro) Mouse IgG1 Anmelden zum Anzeigen ALB9 2
1 ABIN205517 FACS IHC (fro) IF Mouse IgG2a Anmelden zum Anzeigen ML5 0
1 ABIN5631323 FACS ICC IF IHC IHC (fro) DyLight 488 Mouse IgG2a kappa Anmelden zum Anzeigen ML5 0
1 ABIN5631325 FACS ICC IF IHC IHC (fro) DyLight 650 Mouse IgG2a kappa Anmelden zum Anzeigen ML5 0
1 ABIN5631324 FACS ICC IF IHC IHC (fro) DyLight 550 Mouse IgG2a kappa Anmelden zum Anzeigen ML5 0
1 ABIN576359 FACS IHC (fro) PE Mouse IgG1 Anmelden zum Anzeigen 0
1 ABIN206117 FACS IHC (fro) Mouse IgG1 Anmelden zum Anzeigen 0
1 ABIN206168 FACS IHC (fro) FITC Mouse IgG1 Anmelden zum Anzeigen 0
1 ABIN298334 FACS IHC (fro) Mouse IgG1 Anmelden zum Anzeigen SN3 0
1 ABIN384548 FACS IHC (fro) WB Mouse IgG1, kappa Anmelden zum Anzeigen SN3 0
1 ABIN211341 FACS IHC (fro) Mouse IgG1 Anmelden zum Anzeigen 0
1 ABIN316591 FACS IHC (fro) Mouse IgG1 Anmelden zum Anzeigen SN3 0
1 ABIN4290968 FACS ICC IF IHC IHC (fro) DyLight 680 Mouse IgG2a kappa Anmelden zum Anzeigen ML5 0

General

Antigen CD24 Molecule (CD24) Antikörper
Reaktivität Human
(272), (193), (25), (4), (1)
Wirt Maus
(212), (168), (73), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CD24 Antikörper ist unkonjugiert
(54), (50), (34), (26), (13), (11), (7), (7), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
(359), (98), (91), (77), (54), (47), (30), (26), (20), (18), (8), (6), (5), (5), (4), (2), (1), (1), (1)
Pubmed 10 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CD24 Antikörper

Target Details CD24 Anwendungsinformationen Handhabung Referenzen für anti-CD24 Antikörper (ABIN238502) Bilder
Produktmerkmale Synonyms: X62 heat stable antigen, HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4antigen
Reinigung Protein G affinity chromatography.
Immunogen Glycoproteins purified from human NALM-1 cell line.
Klon SN3
Isotyp IgG1

Target Details CD24

Produktdetails anti-CD24 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CD24 Antikörper (ABIN238502) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD24 (CD24 Antibody Abstract)
Hintergrund CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4, it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.Synonyms: HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, X62 heat stable antigen
UniProt P25063
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation

Anwendungsinformationen

Produktdetails anti-CD24 Antikörper Target Details CD24 Handhabung Referenzen für anti-CD24 Antikörper (ABIN238502) Bilder zurück nach oben
Applikationshinweise Suitable for Flow Cytometry and Immunohistochemistry (frozen sections).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CD24 Antikörper Target Details CD24 Anwendungsinformationen Referenzen für anti-CD24 Antikörper (ABIN238502) Bilder zurück nach oben
Buffer PBS, pH 7.4 with 15 mM sodium azide as preservative.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Haltbarkeit 12 months

Referenzen für anti-CD24 Antikörper (ABIN238502)

Produktdetails anti-CD24 Antikörper Target Details CD24 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Maliar, Servais, Waks, Chmielewski, Lavy, Altevogt, Abken, Eshhar: "Redirected T cells that target pancreatic adenocarcinoma antigens eliminate tumors and metastases in mice." in: Gastroenterology, Vol. 143, Issue 5, pp. 1375-84.e1-5, 2012

Keller, Rupp, Stoeck, Runz, Fogel, Lugert, Hager, Abdel-Bakky, Gutwein, Altevogt: "CD24 is a marker of exosomes secreted into urine and amniotic fluid." in: Kidney international, Vol. 72, Issue 9, pp. 1095-102, 2007

Chou, Jeng, Lee, Hu, Kao, Lin, Lai, Hu, Yuan: "Cytoplasmic CD24 expression is a novel prognostic factor in diffuse-type gastric adenocarcinoma." in: Annals of surgical oncology, Vol. 14, Issue 10, pp. 2748-58, 2007

Runz, Mierke, Joumaa, Behrens, Fabry, Altevogt: "CD24 induces localization of beta1 integrin to lipid raft domains." in: Biochemical and biophysical research communications, Vol. 365, Issue 1, pp. 35-41, 2007

Schabath, Runz, Joumaa, Altevogt: "CD24 affects CXCR4 function in pre-B lymphocytes and breast carcinoma cells." in: Journal of cell science, Vol. 119, Issue Pt 2, pp. 314-25, 2006

Suzuki, Kiyokawa, Taguchi, Sekino, Katagiri, Fujimoto: "CD24 induces apoptosis in human B cells via the glycolipid-enriched membrane domains/rafts-mediated signaling system." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 9, pp. 5567-77, 2001

Solvason, Kearney: "The human fetal omentum: a site of B cell generation." in: The Journal of experimental medicine, Vol. 175, Issue 2, pp. 397-404, 1992

Fischer, Majdic, Gadd, Knapp: "Signal transduction in lymphocytic and myeloid cells via CD24, a new member of phosphoinositol-anchored membrane molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 2, pp. 638-41, 1990

Barcos, Pollard, Fukukawa, Seon: "Follicular mantle zone cell subpopulations detected by monoclonal antibody SN3." in: Hematological oncology, Vol. 4, Issue 4, pp. 251-9, 1987

Fukukawa, Matsuzaki, Haruta, Hara, Seon: "New monoclonal antibodies SN3, SN3a, and SN3b directed to sialic acid of glycoprotein on human non-T leukemia cells." in: Experimental hematology, Vol. 14, Issue 9, pp. 850-5, 1986