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anti-Mouse (Murine) Galanin Antikörper:
anti-Human Galanin Antikörper:
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Human Polyclonal Galanin Primary Antibody für ELISA, IHC - ABIN4313189
Sugimoto, Seki, Shimizu, Kikkawa, Tsukada, Shimada, Sasaki, Hanazawa, Okamoto, Hata: The galanin signaling cascade is a candidate pathway regulating oncogenesis in human squamous cell carcinoma. in Genes, chromosomes & cancer 2008
Galanin, acting via the GAL1 receptor and Gi -coupled signalling in L and K cells, is a potent inhibitor of GLP-1 and GIP secretion
Galanin released by cancer induces neuritogenesis, facilitating perineural invasion.
Study shows that LIF-treated postmitotic oligodendrocytes secrete a number of neuropeptides, in particular galanin, at the mRNA and peptide level, and galanin itself was shown to be a survival factor for oligodendrocytes
Results suggest that GAL is a regulator of myelination, as demonstrated by MBP synthesis, and may be one of the myelination promoters
Oleuropein protects mice from gh-fat diet induced adiposity by upregulation of genes involved in WNT10b-mediated signaling and downregulation of genes involved in galanin-mediated signaling cascades.
medial preoptic area galanin neurons emerge as an essential regulatory node of male and female parenting behaviour and other social responses
Analysis of the gene proximal region using EMSA and ChIP assays showed that CREB protein interacts with the galanin promoter both in vitro and in vivo. Additional EMSA analysis revealed that an SP1 consensus site mediated protein-DNA complex formation.
The expression of mRNA galanin is increased following chronic restraint stress.
These results suggest that sertraline-related galanin induction in ventral dentate gyrus may play an important role in therapeutic mechanisms for depression.
extended perifornical area galanin-LepRb neurons galanin acts inhibitory rather than orexigenic
The results suggest that neither galanin expression, nor the galanin-dependent subpopulation of sensory neurons is required for itch-related behaviours.
Galanin transcript expression increased significantly in male mouse major pelvic ganglia neurons after 72 h in explant culture & 72 h after unilateral transection of the cavernous nerve.
results indicate normal cholinergic responses and innervation of the sweat glands in galanin knockout mice, they also demonstrate that galanin plays a role in regulating the sudomotor activity in response to thermal stimulation
GAL is a promising next-generation target for the treatment of MS.
Galanin opposes the actions of morphine which leads to opiate dependence and withdrawal, an effect that is mediated via GalR1
Subpopulations of kisspeptin neurons express galanin and met-enkephalin in the rostral periventricular region of the hypothalamus.
These data showed that the galanin system is regulated by repeated electroconvulsive stimulation in brain regions involved in monoaminergic neurotransmission and stress modulation.
examined the role of galanin signaling in nicotine reward by testing the effects of nicotine in mice lacking galanin peptide (GAL-/-) as compared to wild-type (GAL+/+) controls
Galanin, a potent inhibitor of pancreatic bicarbonate secretion, is involved in the induction and progression of cerulein-induced experimental acute pancreatitis.
Data show that the galanin system is regulated by repeated electroconvulsive stimulation in a number of brain regions implicated in seizure regulation and depression.
Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion.