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anti-Human BMP6 Antikörper:
anti-Rat (Rattus) BMP6 Antikörper:
anti-Mouse (Murine) BMP6 Antikörper:
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Human Polyclonal BMP6 Primary Antibody für IHC (p), WB - ABIN388456
Olavesen, Bentley, Mason, Stephens, Ragoussis: Fine mapping of 39 ESTs on human chromosome 6p23-p25. in Genomics 1998
Show all 5 Pubmed References
The present study demonstrated that BMP6 may protect retinal pigment epithelial cells from oxidative stress injury to a certain extent, which may be associated with alterations in the MAPK (zeige MAPK1 Antikörper) signaling pathway.
Synergistic effects of BMP-2 (zeige BMP2 Antikörper), BMP-6 or BMP-7 (zeige BMP7 Antikörper) with human plasma fibronectin (zeige FN1 Antikörper) onto hydroxyapatite coatings.
Study demonstrated that the mesenchymal epithelial/myoepithelial potential of transdifferentiation of the luminal cells that make up the proliferative units is certified by the immunohistochemical expression of some BMP6 purely mesenchymal protein cells.
both bone morphogenetic protein 2 (BMP2 (zeige BMP2 Antikörper)) and BMP6 are proangiogenic in vitro and ex vivo and that the BMP type I receptors, activin receptor-like kinase 3 (ALK3 (zeige BMPR1A Antikörper)) and ALK2 (zeige ACRV1 Antikörper), play crucial and distinct roles in this process.
Plasma BMP6 was significantly increased in chronic heart failure patients.
Our results independently add further evidence to the role of BMP6 mutations as likely contributing factors to late-onset moderate IO unrelated to mutations in the established five HH genes.
Further investigation on clinical ESCC samples and non-tumorous adjacent tissue found that tumors with triple-positive BMP6, ALK2 (zeige ACRV1 Antikörper) and BMPRII (zeige BMPR2 Antikörper) had deeper growth than tumors with only BMP6 expression
study shows that patients with CRA (zeige MTMR11 Antikörper) had high expression of BMP6 and hepcidin (zeige HAMP Antikörper) and low expression of s-HJV (zeige HFE2 Antikörper). BMP6 was found to be negatively correlated with s-HJV (zeige HFE2 Antikörper); both regulate hepcidin (zeige HAMP Antikörper) expression and play important roles in the development of anemia.
the combined delivery of VEGF (zeige VEGFA Antikörper) and BMP-6 to the bone defect significantly enhanced bone repair through the enhancement of angiogenesis and the differentiation of endogenously recruited MSCs into the bone repair site.
BMP-6 upregulates somatostatin receptor actions, leading to reduction of GnRH-induced secretion of luteinizing hormone.
Report temporal regulation of BMP6 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.
study revealed that only BMP-6 was able to induce bone formation at the used dose and that the addition of IGF-1 (zeige IGF1 Antikörper) contributed to an increase of the mineralization in the implants. Hence, the combination of BMP-6 with IGF-1 (zeige IGF1 Antikörper) might be a better alternative than BMP-2 (zeige BMP2 Antikörper) for orthopedic surgery or bone tissue engineering approaches.
These data suggest that, in Hjv (zeige HFE2 Antikörper)(-/-) females, Bmp6 can provide a signal adequate to maintain hepcidin (zeige HAMP Antikörper) to a level sufficient to avoid extrahepatic iron loading.
The data demonstrate that endothelial cells are the predominant source of BMP6 in the liver and support a model in which endothelial cells BMP6 has paracrine actions on hepatocyte hemojuvelin (zeige HFE2 Antikörper) to regulate hepcidin (zeige HAMP Antikörper) transcription and maintain systemic iron homeostasis.
In summary, our data suggest that in obstructive nephropathy atrophy increases and fibrosis decreases with age and that this relates to increased BMP signaling, most likely due to higher BMP6 and lower CTGF (zeige CTGF Antikörper) expression.
Western blot analysis demonstrated that following BMP2 (zeige BMP2 Antikörper) and BMP7 (zeige BMP7 Antikörper) cotransfection of MC3T3E1 cells, the protein expression levels of BMP2 (zeige BMP2 Antikörper), BMP4 (zeige BMP4 Antikörper), BMP6, BMP7 (zeige BMP7 Antikörper), BMP9 (zeige GDF2 Antikörper) and Wnt3a (zeige WNT3A Antikörper) were increased compared with control cells
In Bmp6-/- mice, iron activated endogenous compensatory mechanisms of other BMPs that were not sufficient for preventing hemochromatosis (zeige HFE Antikörper) and bone loss.
BMP6 expression levels may have potential as predictive markers for the progression of non-alcoholic liver disease.
The expression of BMP6 in periodontal ligaments may contribute to interaction between the tooth and bone during the eruption and anchoring process.
BMP-6 secreted by prostate cancer cells induces IL-6 (zeige IL6 Antikörper) expression in macrophages; IL-6 (zeige IL6 Antikörper), in turn, stimulates the neuroendocrine differentiation of prostate cancer cells.
these data highlight a therapeutically innovative role for BMP6 by providing a means to enhance the amount of myogenic lineage derived brown fat.
High BMP6 expression is associated with cystic ovarian disease.
BMP6 and oxidized low-density lipoprotein independently and synergistically induced osteogenic differentiation and mineralization in vascular endothelial cells.
BMP-6 mRNA is increased during transition from primordial to primary/secondary follicles in the goat ovaries.
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
bone morphogenetic protein 6
, VG-1-related protein
, Vg1-related sequence
, vegetal related growth factor (TGFB-related)
, vegetal-related (TGFB related) cytokine
, bone morphogenic protein 6