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anti-Human BMP2 Antikörper:
anti-Mouse (Murine) BMP2 Antikörper:
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Human Polyclonal BMP2 Primary Antibody für IHC (p), ELISA - ABIN3043489
Tian, Sun, Zhang, Gao, Fu, Yang: Construction and expression of a bicistronic vector containing human bone morphogenetic protein 2 and vascular endothelial growth factor-165 genes in vitro. in Chinese medical journal 2009
Show all 22 Pubmed References
Human Polyclonal BMP2 Primary Antibody für IF (p), IHC (p) - ABIN730903
Huang, Zou, Shi, Zhang, Pen, Zhang, Gao, Wang: The effect of electroacupuncture on the extracellular matrix synthesis and degradation in a rabbit model of disc degeneration. in Evidence-based complementary and alternative medicine : eCAM 2014
Show all 9 Pubmed References
Human Polyclonal BMP2 Primary Antibody für IHC (p), IHC - ABIN446957
Yeom, Kim, Lee, Zhang, Lee, Hahm, Sohn, Lee: Effects of laser acupuncture on longitudinal bone growth in adolescent rats. in Evidence-based complementary and alternative medicine : eCAM 2013
Show all 8 Pubmed References
Human Monoclonal BMP2 Primary Antibody für ELISA - ABIN513751
Freire, You, Kook, Choi, Zadeh: Antibody-mediated osseous regeneration: a novel strategy for bioengineering bone by immobilized anti-bone morphogenetic protein-2 antibodies. in Tissue engineering. Part A 2011
Show all 6 Pubmed References
Human Polyclonal BMP2 Primary Antibody für IF, IHC (p) - ABIN2477681
Wendt, Homberg: Immunocytochemistry of dopamine in the brain of the locust Schistocerca gregaria. in The Journal of comparative neurology 1992
Show all 4 Pubmed References
Human Polyclonal BMP2 Primary Antibody für ELISA, WB - ABIN2477682
Kimura, Matsuo, Shibuya, Nakashima, Taga: BMP2-induced apoptosis is mediated by activation of the TAK1-p38 kinase pathway that is negatively regulated by Smad6. in The Journal of biological chemistry 2000
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Human Polyclonal BMP2 Primary Antibody für FACS, WB - ABIN657779
Liu, Zhao, Chen, Shi, Yuan: RUNX2 polymorphisms associated with OPLL and OLF in the Han population. in Clinical orthopaedics and related research 2010
Show all 5 Pubmed References
Human Polyclonal BMP2 Primary Antibody für IHC, IHC (p) - ABIN4284884
Bridgewater, Mayo, Evanson, Whitt, Dean, Yates, Holden, Schmidt, Fox, Dhunghel, Steed, Adam, Nichols, Loganathan, Barrow, Hancock: A novel bone morphogenetic protein 2 mutant mouse, nBmp2NLS(tm), displays impaired intracellular Ca2+ handling in skeletal muscle. in BioMed research international 2013
Human Polyclonal BMP2 Primary Antibody für IHC, IHC (p) - ABIN4284883
Cordner, Friend, Mayo, Badgley, Wallmann, Stallings, Young, Miles, Edwards, Bridgewater: The BMP2 nuclear variant, nBMP2, is expressed in mouse hippocampus and impacts memory. in Scientific reports 2017
This work indicates that NELL-1 (zeige NELL1 Antikörper), HMGB1 (zeige HMGB1 Antikörper), and CCN2 (zeige CTGF Antikörper) might enhance bone defect healing via the recruitment of endogenous cells and induction of vascularization and act via different processes than BMP2.
Serum BMP2 and Smad4 (zeige SMAD4 Antikörper) levels in patients with senile osteoporotic fracture were significantly lower than those in normal controls
conclude that SUMO3 (zeige SUMO3 Antikörper)-tagged hBMP2 is more suited for generation of soluble form of the protein and addition of SUMO3 (zeige SUMO3 Antikörper) tag does not affect the functional activity of hBMP2
The present study identified a change in miR (zeige MLXIP Antikörper)-22, miR (zeige MLXIP Antikörper)-140, and BMP-2 expression in the synovial fluid of patients with osteoarthritis before and after arthroscopic debridement.
The study revealed an enhanced sensitivity of aortic valve interstitial cells to osteogenic inductors in aortic stenosis patients, which indicates probable implication of OPN (zeige SPP1 Antikörper), OPG (zeige TNFRSF11B Antikörper), and BMP2 genes in pathogenesis of aortic valve calcification.
In contrast to BMP-2, BMP-7 (zeige BMP7 Antikörper) concomitantly inhibited the expression of profibrotic genes
The binding free energies indicate that ALK-3 (zeige BMPR1A Antikörper) preferably binds to BMP-2 instead of BMP-9 (zeige GDF2 Antikörper). The structural analysis shows that ALK-3 (zeige BMPR1A Antikörper) binding with BMP-2 occurs in a perfectly symmetry pathway, whereas this symmetry is lost for possible ALK-3 (zeige BMPR1A Antikörper) interactions with BMP-9 (zeige GDF2 Antikörper)
The results demonstrate the efficacy of HPP (zeige SPTA1 Antikörper)-GC hydrogel in minimizing the diffusive loss of rhBMP-2 from the implantation site, compared to the collagen hydroxyapatite scaffold.
The in vitro results suggest that altered BMP2 regulatory function at rs1884302 may contribute to the etiology of sagittal nonsyndromic craniosynostosis. The in vivo results indicate that differences in regulatory activity depend on the presence of a C or T allele at rs1884302.
Collectively, according to our study, rhIL-6 could induce the extracellular calcification and osteogenic differentiation of human artery smooth muscle cells through upregulating endogenous BMP2 in vitro. This may be one of the underlying mechanisms of the overwhelming vascular calcification in rheumartoid arthritis.
widespread myocardial Bmp2 and endocardial Notch (zeige NOTCH1 Antikörper) signaling drive presumptive ventricular endocardium to differentiate into valve endocardium
BMP-2 can enhance HUVEC proliferation, migration and angiogenesis through P38, ERK and Akt/m-TOR pathway.
CTGF (zeige CTGF Antikörper) and BMP2 are induced following myocardial ischemia in mice and humans.
Results indicate that Notch (zeige NOTCH1 Antikörper) signaling induces cell cycle arrest and thereby initiates chondrocyte cell enlargement via bone morphogenetic protein 2 (BMP2) signaling.
Collectively, our findings indicate that CBFA2T2 (zeige CBFA2T2 Antikörper) is required for BMP-2-induced osteogenic differentiation of MSCs through inhibition of EHMT1 (zeige EHMT1 Antikörper)-mediated histone methylation at Runx2 (zeige RUNX2 Antikörper) promoter.
The data suggest that SDF-1beta provides synergistic effects supporting BMP-2-induced, BMSC-mediated bone formation and appears suitable for optimization of bone augmentation in combination therapy protocols.
study revealed that only BMP-6 (zeige BMP6 Antikörper) was able to induce bone formation at the used dose and that the addition of IGF-1 (zeige IGF1 Antikörper) contributed to an increase of the mineralization in the implants. Hence, the combination of BMP-6 (zeige BMP6 Antikörper) with IGF-1 (zeige IGF1 Antikörper) might be a better alternative than BMP-2 for orthopedic surgery or bone tissue engineering approaches.
BMP2 may induce osteogenic differentiation.
Increased bone mass in Crmp4 (zeige DPYSL3 Antikörper)(-/-) mice was associated with enhanced BMP2 signaling and BMP2-induced osteoblast differentiation in Crmp4 (zeige DPYSL3 Antikörper)(-/-) osteoblasts (OBs (zeige LEP Antikörper)).
Deletion of the "ultra-conserved sequence" within the 3'UTR of the Bmp2 was associated with elevated Bmp2 mRNA and BMP signaling levels, reduced fitness, and embryonic malformations.
Bone morphogenetic protein inhibition is sufficient for neural induction in vivo, and that in the absence of ventral BMPs, Spemann organizer signals are not required for brain formation.
Bmp antagonists and morpholinos designed against Bmp4, Bmp2, and Bmp7 demonstrate that Bmp signaling is critical for ventral, but not dorsoanterior endoderm formation
High BMP2 expression is associated with cystic ovarian disease.
both FSH (zeige BRD2 Antikörper) and BMP-2 reduced follicular mRNA expression of GDF9 (zeige GDF9 Antikörper) and NLRP5 (zeige NLRP5 Antikörper) when compared to follicles cultured in media containing only FSH (zeige BRD2 Antikörper)
The BMP2/4 (zeige BMP4 Antikörper) ligand and receptor system presides within bovine trophectoderm prior to uterine attachment.
concluded that a bone morphogenetic protein (BMP)-signaling system, consisting of BMP2, BMP4, type II and I receptors, is present in bovine antral follicles and plays a role in development and functioning of follicles rather than oocyte maturation
The transfecting capability of a BMP-2 specific vector is examined and supports the idea that BMP-2 might diminish osseointegration and implant fixation.
While BMP2 expression begins at (pregastrulation) stage 1 in the hypoblast, BMP4 (zeige BMP4 Antikörper) expression commences--distinctly delayed compared to the mouse--diffusely at (pregastrulation) stage 2; from stage 3 onwards.
Maxillary sinus floor elevation using BMP-2 gene-modified bone marrow stromal cells and TCP (zeige ABP Antikörper) in rabbits
Data show that BMP-2, BMP-4 (zeige BMP4 Antikörper), and BMP-7 (zeige BMP7 Antikörper), noggin (zeige NOG Antikörper), and chordin (zeige CHRD Antikörper) were colocalized in rimming osteoblasts, osteoclasts, and chondrocytes.
BMP2 is not suitable to regenerate osteochondral lesions completely
High yield isolation of BMP-2 from bone and in vivo activity of a combination of BMP-2/TGF-beta1 (zeige TGFB1 Antikörper).
Report temporal regulation of BMP2 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.
Regional variation of periosteal activity at the mandibular ramus is regulated by differential induction of BMP2.
The effects of soy- and cow's milk-based formulas compared to nursing on bone development through BMP2 expression in neonatal pigs are reported.
The effect of bone morphogenetic protein (BMP) 12 and BMP2 expression on differentiation of bone marrow-derived mesenchymal stem cells and superficial digital flexor tenocytes is reported.
Study found that BMP-2 (zeige BMP4 Antikörper) is negatively regulated by miR (zeige MYLIP Antikörper)-140 during early embryogenesis and bone development in zebra fi sh.
Structures of Bmp2a, Bmp2b (zeige BMP4 Antikörper), Bmp4 (zeige BMP4 Antikörper) and Bmp16 were found to be remarkably similar; with residues involved in receptor binding being highly conserved.
bmp2a is a crucial player in the specification of the ventral pancreatic bud in zebrafish embryos.
results indicate that both the induction of a photoreceptor fate and the interaction with Notch (zeige NOTCH1 Antikörper) relies on a canonical BMP/Smad5 (zeige SMAD5 Antikörper) pathway
Mypt1 (zeige PPP1R12A Antikörper) mediates coordination between mesoderm and endoderm cell movements in order to carefully position the liver primordium such that it receives a Bmp2 (zeige BMP4 Antikörper) signal that is essential for liver formation
The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation.
, bone morphogenetic protein 2A
, bone morphogenetic protein 2 B
, bone morphogenetic protein 2-B
, bone morphogenetic protein 2
, Bone morphogenetic protein 2
, bone morphogenetic protein 2-like
, bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A)