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Human SEMA3A ELISA Kit für Sandwich ELISA - ABIN481720
Vadasz, Haj, Halasz, Rosner, Slobodin, Attias, Kessel, Kessler, Neufeld, Toubi: Semaphorin 3A is a marker for disease activity and a potential immunoregulator in systemic lupus erythematosus. in Arthritis research & therapy 2012
Show all 4 Pubmed References
Human SEMA3A ELISA Kit für Sandwich ELISA - ABIN858267
Treps, Edmond, Harford-Wright, Galan-Moya, Schmitt, Azzi, Citerne, Bidère, Ricard, Gavard: Extracellular vesicle-transported Semaphorin3A promotes vascular permeability in glioblastoma. in Oncogene 2015
Significant genetic risk for Hirschsprung disease (HSCR (zeige EDNRB ELISA Kits)) was imparted by rs2435357 and rs2506030 at RET (zeige RET ELISA Kits) and by rs12707682 at SEMA3 in a Chinese population. No evidence was found of a genetic association between HSCR (zeige EDNRB ELISA Kits) and either of the NRG1 (zeige NRG1 ELISA Kits) SNPs rs7835688 and rs16879552, at either allele or genotype level.
rs139438618 at the semaphorin 3A locus was significantly associated with Alcohol Dependence and Major Depression comorbidity in African Americans. There was no significant association identified in European American participants.
Serum level of Sema3A taken from diagnosed celiac without gluten-free diet was higher significantly than healthy controls.
Sema3A serum levels and the expression of sema3A on Tregs was significantly lower in patients with moderate to severe asthma when compared to healthy individuals.
Sema3a-Nrp2 (zeige NELL2 ELISA Kits) signaling along an unrecognized pancreatic developmental axis constitutes a chemoattractant system essential for generating the hallmark morphogenetic properties of pancreatic islets.
EV-delivered Sema3A orchestrates loss of barrier integrity in glioblastoma
IL6 (zeige IL6 ELISA Kits) underexpression is associated with Breast Cancer.
We also demonstrate that the effects of RET (zeige RET ELISA Kits) and NRG1 (zeige NRG1 ELISA Kits) are universal across European and Asian ancestries. In contrast, we detected a European-specific association of a low-frequency variant, rs80227144, in SEMA3. Conditional analyses on the lead SNPs revealed a secondary association signal, corresponding to an Asian-specific, low-frequency missense variant encoding RET (zeige RET ELISA Kits) p.Asp489Asn
Semaphorin3A serum concentrations were similar in ankylosing spondylitis patients and controls and were not altered on treatment in anti-TNF (zeige TNF ELISA Kits) agents.
The self-renewal ability abolished by Sema3a knockdown could not be recovered by exogenous addition of recombinant SEMA3A. In addition, the activity of mammalian target of rapamycin (zeige FRAP1 ELISA Kits) complex 1 (mTORC1) and the expression of its substrate p70S6K1 (zeige RPS6KB1 ELISA Kits) were also decreased. These results demonstrate that Sema3a is a potential therapeutic target in eradication of CSCs.
Sema3a-Nrp2 (zeige NRP2 ELISA Kits) signaling along an unrecognized pancreatic developmental axis constitutes a chemoattractant system essential for generating the hallmark morphogenetic properties of pancreatic islets.
These data suggest that both Nrp1 (zeige NRP1 ELISA Kits) and Sema3a are expressed in the cochlea during time points when spiral ganglion cell begin to innervate the organ of Corti.
We show that PTP-3, a LAR (zeige PTPRF ELISA Kits) homolog in Caenorhabditis elegans, participates in Sema2A-regulated axon guidance. PTPdelta, a member of vertebrate LAR (zeige PTPRF ELISA Kits) class PTPs (zeige PTS ELISA Kits), is involved in Sema3A-regulated cortical dendritic growth. In Sema3A signaling, PTPdelta activates Fyn (zeige FYN ELISA Kits) and Src (zeige SRC ELISA Kits) kinases by dephosphorylating their C-terminal Tyr (zeige TYR ELISA Kits) residues.
Investigated the effects of BotoxA-induced paralysis on the sprouting capacity of neuromuscular junctions (NMJs) in the K108N-SEMA3A mutant, and observed no change in the differential neuronal plasticity found at NMJs on fast-fatigable or slow muscle fibers due to the presence of the SEMA3A mutant protein.
The aim was to elucidate whether ectopic muscles are a result of misguidance of myoblast precursors due to the loss of Sema3A-Npn-1 (zeige NRP1 ELISA Kits) signaling.
These findings suggest that by interacting with PlexA4 (zeige PLXNA4 ELISA Kits), TrkA (zeige NTRK1 ELISA Kits) plays a crucial role in redirecting local Sema3A signaling to retrograde axonal transport, thereby regulating dendritic GluA2 (zeige GRIA2 ELISA Kits) localization and patterning.
Findings indicate that Rho and ROCK knockout may improve the behavior of mice and prevent MPTP (zeige PTPN2 ELISA Kits)-induced dopaminergic neurons damage by regulating Sema3A, PlexinA and NRP-1 (zeige NRP1 ELISA Kits) in a mouse model of Parkinson's disease.
Sema3A signaling exerts its oncogenic effect by promoting an mTORC1-mediated metabolic shift from oxidative phosphorylation to aerobic glycolysis.
Semaphorin 3A (Sema3A) is a protein secreted during the development of the nervous system that acts as a cue for axon induction .
this paper shows that Nav1.7 (zeige SCN9A ELISA Kits), by coupling with CRMP1 (zeige CRMP1 ELISA Kits), mediates the axonal retrograde signaling of Sema3A in axonal guidance
This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
, semaphorin 3A
, collapsin 1
, semaphorin D
, semaphorin III
, semaphorin L
, sema D
, sema III
, Semaphorin 3a
, sema domain, immunoglobulin domain (Ig), short basic domain, sec