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JMY Antigen Profile
Beschreibung des Gens
Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics.
Alternative names and synonyms associated with JMY
junction mediating and regulatory protein, p53 cofactor (JMY) ELISA Kit
junction mediating and regulatory protein, p53 cofactor (jmy) ELISA Kit
junction-mediating and regulatory protein (Jmy) ELISA Kit
WHDC1L3 ELISA Kit
Bezeichner auf Proteinebene für JMY
junction mediating and regulatory protein, p53 cofactor
, junction-mediating and regulatory protein
, junction-mediating and -regulatory protein
, WAS protein homology region 2 domain containing 1-like 3
, p300 transcriptional cofactor JMY