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An analysis of eight structures of mitochondrial bc(1) with bound quinol oxidation (Q(o)) site inhibitors revealed that the presence of inhibitors causes a bidirectional repositioning of the cd1 helix in the cytochrome b subunit.
mt-Cytb mutations were studied in a mouse cultured cell model. Complex III assembly was impeded and caused a severe reduction in the amount of Complex I.
The heteroplasmy level of some mutations in gene MT-CYB among women with asymptomatic atherosclerosis
The effects of mutation in mitochondrially encoded cytochrome b are reviewed.
Mitochondrial mutation m.15804T>C in the mtCYB gene in a family with fibromyalgia is associated with NLRP3 (zeige NLRP3 Proteine)-inflammasome activation.
These results indicate that miR (zeige MLXIP Proteine)-151a-5p may participate in the regulation of cellular respiration and ATP production through targeting Cytb.
This study suggests that, in part, polymorphisms in the MT-ATP6 (zeige MT-ATP6 Proteine) and MT-CYB genes may contribute to the unexpected fertilization failure.
The polymorphisms of CYTB as a very useful DNA marker were significantly different between different geographical Uyghur
Significant elevation of ERalpha (zeige ESR1 Proteine) and MTCYB transcript levels in premenopausal leiomyomas and its association with ERalpha (zeige ESR1 Proteine), -397 CC genotype suggests the mitochondrial-mediated role of estrogen as the promoter of leiomyoma tumorigenesis.
Data show that homoplasmic G6709A (MT-CO1) and G14804A (MT-CYB) alterations cause amino acid changes in the highly conserved residues.
mitocryptide-2 (MCT-2) and its human homolog hMCT-2 are cryptides that activate neutrophils
The other proband had a non-synonymous G15221A mutation in the cytochrome b gene.
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity).