TGFA Protein

Produktnummer ABIN935809

Produktdetails

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Sequenz: VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA

Produktmerkmale: Purified recombinant Human TGF alpha protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is ? 0.2 ng/mL, corresponding to a specific activity of ? 5 x 10^6 units/mg.

Reinheit: > 98 % pure

Endotoxin-Niveau: < 0.1 ng per μg (1 EU/μg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Kommentare:

Biological activity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is approx. 0.2 ng/mL, corresponding to a specific activity of approx. 5 x 10^6 units/mg.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.

Buffer: Supplied lyophilized with no additives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Antigendetails

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Andere Bezeichnung: TGF alpha (TGFA Produkte)

Synonyme: TFGA Protein, LOC100009482 Protein, TGF alpha Protein, TGFA Protein, wa-1 Protein, wa1 Protein, RATTGFAA Protein, TGFAA Protein, NV15606 Protein, si:ch211-10e8.7 Protein, transforming growth factor alpha Protein, transforming growth factor alpha L homeolog Protein, transforming growth factor-alpha Protein, transforming growth factor, alpha Protein, TGFA Protein, TGF-A Protein, Tgfa Protein, tgfa.L Protein, LOC100121300 Protein, LOC100009150 Protein, tgfa Protein

Hintergrund: TGF alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF alpha induces transformation anchorage independence in cultured cells. Human, Mouse and rat TGF alpha are cross-species reactive. Recombinant human TGF alpha is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40 % sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
Alternative Names: TGF-alpha protein, TGFa protein, Transforming Growth Factor alpha protein, TGF a protein, TGFalpha protein

Molekulargewicht: 5.5 kDa

Pathways: NF-kappaB Signalweg, RTK Signalweg, EGFR Signaling Pathway