Purified recombinant Human LAG 1 protein Expression System: E.coli Bioactivity: Determined by it's ability to chemoattract CCR5 transfected cells using a concentration of 0.1-10.0 ng/mL
LAG-1 is CC chemokine that signals through the CCR5 receptor. LAG-1 is identical to MIP-1beta (ACT II isotype) except for two amino acid substitutions, arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV suppressive factor. Alternative Names: LAG-1 protein, LAG 1, T-cell activiation-2 protein, HC21 protein, LAG 1, Lymphocyte Activation Gene-1 protein, CCL4L1 protein, LAG-1, LAG-1 protein, ACT-2 protein, LAG 1 protein