Vascular Endothelial Cell Growth Factor 165 (VEGF165) (Active) Protein

Details zu Produkt Nr. ABIN781101
Proteinname
Spezies
Ratte (Rattus)
7
3
2
Quelle
Escherichia coli (E. coli)
10
1
1
Protein-Typ
Recombinant
Biologische Aktivität
Active
Applikation
In vitro Assay (in vitro), In vivo Studies (in vivo), ELISA, Western Blotting (WB)
Optionen
Sequenz MAPTTEGEQK AHEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNVTMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
Spezifität Recombinant rat VEGF-165 is a disulfide linked homodimer, containing two 165 amino acids chains, with a total molecular weight of 38.8 kDa.
Reinheit ≥ 95%
Sterilität 0.2 μm filtered
Endotoxin-Niveau ≤ 1.00 LAL (EUs/ug)
Biological Activity Comment
  • Bioactivity Assay: HUVEC proliferation
  • Bioactivity Acceptance Criteria ED50 (ng/ml): 8 ng/mL
  • Bioactivity Acceptance Criteria (Units/mg): 1.3 x 10^5 units/mg
Proteinname
Hintergrund Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.

Alternate Names: VEGF-A, VPF, glioma-derived endothelial cell mitogen
Molekulargewicht Monomer: 19.4/38.8 MW Monomer/Total (kDa)
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Kommentare

Media Components: Luria Broth

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Sterile water at 0.1 mg/mL
Buffer Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing : 10 mM sodium phosphate,  pH 7.5
Konservierungs-mittel Without preservative
Handhabung Centrifuge vial before opening.
Lagerung 4 °C,-20 °C,-80 °C
Informationen zur Lagerung 12 months from date of receipt when stored at -20°C to-80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.
Haltbarkeit 12 months
Bilder des Herstellers
 image for Vascular Endothelial Cell Growth Factor 165 (VEGF165) (Active) protein (ABIN781101) Vascular Endothelial Cell Growth Factor 165 (VEGF165) (Active) protein
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