Nanos Homolog 1 Protein (NANOS1) (AA 1-267) (His tag)

Produktnummer ABIN7558403

Dieses Recombinant Nanos Homolog 1-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für Nanos Homolog 1 Protein (NANOS1) (AA 1-267) (His tag) (ABIN7558403)

Target: Nanos Homolog 1 (NANOS1)

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Produktdetails

Proteineigenschaft: AA 1-267

Aufreinigungstag / Konjugat: Dieses Nanos Homolog 1 Protein ist gelabelt mit His tag.

Verwendungszweck: Predefined custom protein recombinant Nanos1 Protein expressed in mammalian cells.

Sequenz: MEAFPWAPRS PRRARAPAPM ALVPSARYVS ASGPVHPQPF SSWNDYLGLA TLITRASDRG SPHEGPGPTA AGPTMGPPED DEDDDGEEPE AGGRYLGGAL ELRALELCAG PAEPGLLEER FAELNPFAGR AAAVLLGCAP TASTTAAAAS TAEVTPREEP SPAWAAEPRL HAASGATAAR LLKPELQVCV FCRNNKEAVA LYTTHILKGP DGRVLCPVLR RYTCPLCGAS GDNAHTIKYC PLSKVPPPTV RPPPRSNRDS LPSKKLR Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: Nanos Homolog 1 (NANOS1)

Andere Bezeichnung: Nanos1

Hintergrund: Nanos homolog 1 (NOS-1),FUNCTION: May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion (By similarity). Not essential for normal development. {ECO:0000250, ECO:0000269|PubMed:12834871}.

Molekulargewicht: 28.2 kDa

UniProt: Q80WY3

AlphaFold: Q80WY3

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction