SLC22A13 Protein (AA 1-551) (His tag)

Produktnummer ABIN7557903

Recombinant SLC22A13-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für SLC22A13 Protein (AA 1-551) (His tag) (ABIN7557903)

Target: SLC22A13 (Solute Carrier Family 22 (Organic Anion Transporter), Member 13 (SLC22A13))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Produktdetails

Proteineigenschaft: AA 1-551

Aufreinigungstag / Konjugat: Dieses SLC22A13 Protein ist gelabelt mit His tag.

Verwendungszweck: Predefined custom protein recombinant Slc22a13 Protein expressed in mammalian cells.

Sequenz: MAQFAQVMAE VGDFGRFQVR LTILMGIPNF LAAFFIFGQV FMVLDEAHHC SVSWVKNHTF NLSAAEQLAI SIPNDTAGRP ESCLMFRPPP DSASLEDILS HRFNETQACD SGWDYPENRP QSLKKEFDLV CDRKNLKKTS QSVFMAGLLV GALVFGPVCD WIGRRPSLLM QVLLSGITSM ATAFVSSFEL YLALRFVLAT ANAGFLLSTN VLISEWVGPS WRTQAVVLAQ SNVALGQMVL AGLAYGVRNW RLLQITGTAP VLLLFFYFWV LPESPRWLLS QGRTEEAKQL VQKAALVNGR PLSPELLNQL VPEKTGPSGN ALDLFRHPHL RKVTLILIAV WFVDSLVYYS LSFQVGDFGL DIYVTQLIFG AVEMPGRFLS VLMMEKLGRK WSQLCTLTLA GIMYIIIIFI PGDLPTVVTV LAVVGKFASA AAFTISYVYT AELFPTIIRQ TGMGLVSIFS RVGGIITPLV MLLEQYHQAI PMVIFGSLPI GAGLLCALLP ETRGQTLKDT LQDLEQGLPA GSHKTAPQRQ DMEALGRTSS VRVAVVKSSY F Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: SLC22A13 (Solute Carrier Family 22 (Organic Anion Transporter), Member 13 (SLC22A13))

Andere Bezeichnung: Slc22a13

Hintergrund: Solute carrier family 22 member 13 (Organic anion transporter 10) (OAT10) (Organic cation transporter-like 3) (ORCTL-3),FUNCTION: Anion antiporter that mediates the transport of orotate and nicotinate in exchange for organic or inorganic anions (PubMed:35144162). Translocates orotate across the apical membrane of proximal tubule epithelial cells. Possibly involved in orotate renal reabsorption and nicotinate intestinal reabsorption (PubMed:35144162). Orotate transport is Cl(-)-dependent (By similarity). {ECO:0000250|UniProtKB:Q9Y226, ECO:0000269|PubMed:35144162}.

Molekulargewicht: 60.7 kDa

UniProt: Q6A4L0

AlphaFold: Q6A4L0