MACROD2 Protein (AA 1-475) (His tag)

Produktnummer ABIN7557312

Recombinant MACROD2-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für MACROD2 Protein (AA 1-475) (His tag) (ABIN7557312)

Target: MACROD2 (MACRO Domain Containing 2 (MACROD2))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Produktdetails

Proteineigenschaft: AA 1-475

Aufreinigungstag / Konjugat: Dieses MACROD2 Protein ist gelabelt mit His tag.

Verwendungszweck: Predefined custom protein recombinant Macrod2 Protein expressed in mammalian cells.

Sequenz: MYPSNKKKKV WREEKERLLK MTLEERRKEY IRDYVSLSTI LSWKEEMKSK GQNDEENTQE APQMKKSLSE KVSLYRGDIT LLEVDAIVNA ANASLLGGGG VDGCIHRAAG PCLLAECRNL NGCETGHAKI TCGYDLPAKY VIHTVGPIAR GHINGSHKED LANCYQSSLK LVKENNLRSV AFPCISTGIY GFPNEPAAVI ALGTIKEWLA KNHQEVDRII FCVFLEVDFK IYKKKMNEFF PVDDNNEGTD ADMKEDSEGP EPKGLSPPHK KSKAKKPESS KDSSEDESGP EEKQTAEEME GQSQEAGGLR FLLRNLLGLI HRDGVNTTPV PSPASEDKAE VHKDEDSAKD DNTVKDSDMT NHSVCDQELP NGQENDSAKS EGKTEAESPS SSMETEDLSP NQEDAAIVEQ PEVIPLIDDQ EAQEGGEAQG KDAPAVFAES QGSSEAENTS GPDVDMNSQV DGVNEPTESL QEDLQ Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: MACROD2 (MACRO Domain Containing 2 (MACROD2))

Andere Bezeichnung: Macrod2

Hintergrund: ADP-ribose glycohydrolase MACROD2 (MACRO domain-containing protein 2) (O-acetyl-ADP-ribose deacetylase MACROD2) (EC 3.5.1.-) ([Protein ADP-ribosylaspartate] hydrolase MACROD2) (EC 3.2.2.-) ([Protein ADP-ribosylglutamate] hydrolase MACROD2) (EC 3.2.2.-),FUNCTION: Removes ADP-ribose from aspartate and glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. {ECO:0000250|UniProtKB:A1Z1Q3}.

Molekulargewicht: 52.1 kDa

UniProt: Q3UYG8

AlphaFold: Q3UYG8