Periostin Protein (POSTN) (AA 22-836) (His tag)

Produktnummer ABIN7491277

Dieses Recombinant Periostin-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für Periostin Protein (POSTN) (AA 22-836) (His tag) (ABIN7491277)

Target: Periostin (POSTN)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Applikation: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Reinheit: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Produktdetails

Proteineigenschaft: AA 22-836

Aufreinigungstag / Konjugat: Dieses Periostin Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human POSTN Protein with C-terminal 6xHis tag

Spezifität: POSTN(Asn22-Gln836) 6xHis tag

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Anwendungsinformationen

Applikationshinweise: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Kommentare:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: Periostin (POSTN)

Andere Bezeichnung: POSTN

Hintergrund: OSF-2,OSF2,PDLPOSTN,PN
This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

Molekulargewicht: predicted molecular mass of 91.8 kDa after removal of the signal peptide. The apparent molecular mass of POSTN-His is 55-100 kDa due to glycosylation.

UniProt: Q15063