NCR3 Protein (AA 19-138) (His-Avi Tag,Biotin)

Produktnummer ABIN7275354

Produktdetails

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 19-138

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses NCR3 Protein ist gelabelt mit His-Avi Tag,Biotin.

Verwendungszweck: Biotinylated Human NKp30/NCR3/CD337 Protein

Sequenz: Leu19-Thr138

Produktmerkmale: Recombinant Biotinylated Human NKp30/NCR3/CD337 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Leu19-Thr138.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Anti-NKp30 Antibody, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human NKp30, His Tag with the EC50 of 30ng/ml determined by ELISA. The affinity constant of 0.330 μM as determined in SPR assay (Biacore T200). See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Andere Bezeichnung: NKp30 (NCR3 Produkte)

Synonyme: MGC133750 Protein, 1C7 Protein, CD337 Protein, LY117 Protein, MALS Protein, NKp30 Protein, Nkp30 Protein, natural cytotoxicity triggering receptor 3 Protein, NCR3 Protein, Ncr3 Protein

Hintergrund: NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells.

Molekulargewicht: 20 kDa. Due to glycosylation, the protein migrates to 26-45 kDa based on Tris-Bis PAGE result.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process