Midkine Protein (AA 23-140) (His tag)

Produktnummer ABIN7275260

Produktdetails

Target: Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))

Protein-Typ: Recombinant

Proteineigenschaft: AA 23-140

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Midkine Protein ist gelabelt mit His tag.

Verwendungszweck: Mouse Midkine Protein

Sequenz: Lys23-Asp140

Produktmerkmale: Recombinant Mouse Midkine Protein is expressed from E.coli with His tag at the N-Terminus.It contains Lys23-Asp140.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in PBS, 350 mM NaCl, 200 mM L-arginine ( pH 7.4).

Lagerung: -80 °C

Informationen zur Lagerung: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))

Andere Bezeichnung: Midkine (MDK Produkte)

Synonyme: ARAP Protein, MK Protein, NEGF2 Protein, Mek Protein, MK-B Protein, PTF-alpha-1 Protein, mdk Protein, midkine Protein, negf2 Protein, RIHB Protein, cb518 Protein, fb79b05 Protein, fj33b02 Protein, fj48a12 Protein, mdk2 Protein, plei2 Protein, wu:fb79b05 Protein, wu:fj33b02 Protein, wu:fj48a12 Protein, MK-A Protein, PTF-alpha-2 Protein, X-PTF-alpha1 Protein, XMK Protein, mdk-a Protein, mdk-b Protein, midkine Protein, midkine L homeolog Protein, midkine (neurite growth-promoting factor 2) Protein, midkine b Protein, midkine S homeolog Protein, MDK Protein, Mdk Protein, mdk.L Protein, mdkb Protein, mdk.S Protein

Hintergrund: Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis.

Molekulargewicht: 14.03 kDa. The protein migrates to 17-20 kDa based on Tris-Bis PAGE result.

UniProt: P12025

Pathways: RTK Signalweg, M Phase, Skeletal Muscle Fiber Development