L1CAM Protein (AA 20-1123) (His tag)

Produktnummer ABIN7275127

Produktdetails

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Protein-Typ: Recombinant

Proteineigenschaft: AA 20-1123

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses L1CAM Protein ist gelabelt mit His tag.

Verwendungszweck: Mouse L1CAM Protein

Sequenz: Ile20-Glu1123

Produktmerkmale: Recombinant Mouse L1CAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile20-Glu1123.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Andere Bezeichnung: L1CAM (L1CAM Produkte)

Synonyme: l1cam-a Protein, CAML1 Protein, CD171 Protein, HSAS Protein, HSAS1 Protein, MASA Protein, MIC5 Protein, N-CAM-L1 Protein, N-CAML1 Protein, NCAM-L1 Protein, S10 Protein, SPG1 Protein, L1 Protein, Hsas Protein, Hyd Protein, NCAML1 Protein, L1 cell adhesion molecule S homeolog Protein, L1 cell adhesion molecule Protein, l1cam.S Protein, L1CAM Protein, L1cam Protein

Hintergrund: L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers.

Molekulargewicht: 125.4 kDa. Due to glycosylation, the protein migrates to 160-180 kDa based on Tris-Bis PAGE result.

UniProt: P11627

Pathways: Synaptic Membrane