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Growth Hormone Receptor Protein (GHR) (AA 27-264) (His tag)

GHR Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274745
  • Target Alle Growth Hormone Receptor (GHR) Proteine anzeigen
    Growth Hormone Receptor (GHR)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 27-264
    Spezies
    • 15
    • 9
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 13
    • 13
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Growth Hormone Receptor Protein ist gelabelt mit His tag.
    Verwendungszweck
    Human GHR/Growth Hormone R Protein
    Sequenz
    Ala27-Tyr264
    Produktmerkmale
    Recombinant Human GHR/Growth Hormone R Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala27-Tyr264.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Growth Hormone Receptor (GHR)
    Andere Bezeichnung
    GHR (GHR Produkte)
    Synonyme
    GHBP Protein, AA986417 Protein, GHR/BP Protein, GHR Protein, ghr Protein, ghr.a Protein, zgc:162141 Protein, growth hormone receptor Protein, growth hormone receptor L homeolog Protein, growth hormone receptor a Protein, GHR Protein, Ghr Protein, ghr.L Protein, ghr Protein, ghra Protein
    Hintergrund
    Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual functions based on its localization in the plasma membrane and nucleus.
    Molekulargewicht
    28.8 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result.
    Pathways
    NF-kappaB Signalweg, JAK-STAT Signalweg, Response to Growth Hormone Stimulus
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