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Endoglin Protein (ENG) (His-Avi Tag)

ENG Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Produktnummer ABIN7274511
  • Target Alle Endoglin (ENG) Proteine anzeigen
    Endoglin (ENG)
    Protein-Typ
    Recombinant
    Spezies
    • 19
    • 10
    • 2
    • 2
    Human
    Quelle
    • 14
    • 8
    • 6
    • 3
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Endoglin Protein ist gelabelt mit His-Avi Tag.
    Sequenz
    Glu26-Gly586
    Reinheit
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human Endoglin, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Anti-Endoglin Antibody, hFc Tag with the EC50 of 13.4ng/ml determined by ELISA. See testing image for detail.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Endoglin (ENG)
    Andere Bezeichnung
    Endoglin (ENG Produkte)
    Synonyme
    ENG Protein, MGC137842 Protein, DKFZp469D0419 Protein, END Protein, HHT1 Protein, ORW1 Protein, AI528660 Protein, AI662476 Protein, CD105 Protein, S-endoglin Protein, endoglin Protein, ENG Protein, Eng Protein
    Hintergrund
    CD105, Endoglin, ENG, ORW, ORW1, END, HHT1,Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.
    Molekulargewicht
    63.7 kDa. Due to glycosylation, the protein migrates to 70-82 kDa based on Tris-Bis PAGE result.
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