HHLA2 Protein (AA 23-344) (Fc Tag)
-
- Target Alle HHLA2 Proteine anzeigen
- HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 23-344
-
Spezies
- Human
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses HHLA2 Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Human B7-H7/HHLA2 Protein
- Sequenz
- Ile23-Asn344
- Produktmerkmale
- Recombinant Human B7-H7/HHLA2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile23-Asn344.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human CD28H, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human B7-H7, hFc Tag with the EC50 of 0.23μg/ml determined by ELISA. The affinity constant of 334 nM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product HHLA2 Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
- Andere Bezeichnung
- B7-H7 (HHLA2 Produkte)
- Synonyme
- B7H7 Protein, HERV-H LTR-associating 2 Protein, HHLA2 Protein, hhla2 Protein
- Hintergrund
- B7-H7, also known as HHLA2 (HERV-H LTR-associating 2), is a member of the B7 family of immune regulatory proteins.Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
- Molekulargewicht
- 63.7 kDa. Due to glycosylation, the protein migrates to 78-100 kDa based on Tris-Bis PAGE result.
-