CHIA Protein (AA 22-476) (His tag)

Produktnummer ABIN7273824

Produktdetails

Target: CHIA (Chitinase, Acidic (CHIA))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-476

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CHIA Protein ist gelabelt mit His tag.

Verwendungszweck: Human AMCase/CHIA Protein

Sequenz: Tyr22-Ala476

Produktmerkmale: Recombinant Human AMCase/CHIA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr22-Ala476.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: CHIA (Chitinase, Acidic (CHIA))

Andere Bezeichnung: AMCase (CHIA Produkte)

Synonyme: chia-a Protein, AMCASE Protein, CHIT2 Protein, TSA1902 Protein, 2200003E03Rik Protein, AMCase Protein, YNL Protein, CHIA Protein, chioIIa Protein, fa55g10 Protein, wu:fa55g10 Protein, zgc:63792 Protein, acidic mammalian chitinase Protein, chitinase, acidic Protein, chitinase, acidic S homeolog Protein, chitinase-M31, acidic Protein, chitinase, acidic 1 Protein, chitinase, acidic.4 Protein, LOC703284 Protein, CHIA Protein, LOC100600050 Protein, chia.S Protein, CHIA-M31 Protein, Chia1 Protein, Chia Protein, chia.4 Protein

Hintergrund: Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans. The chitinase activity of AMCase was found to be causative in allergic inflammation and its expression was found to be induced by interleukin-13. CHIT1-1 is expressed by phagocytic cells and extremely high levels are seen in lysosomal storage diseases. Despite that AMCase expression in the inflammation is under investigation, little is known regarding its regulation during macrophages' full maturation and polarization.

Molekulargewicht: 51.2 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.