SARS-CoV Spike Protein (R667A, Trimer) (His tag)

Produktnummer ABIN7271647

Produktdetails

Target: SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))

Protein-Typ: Recombinant

Proteineigenschaft: R667A, Trimer

Spezies: SARS Coronavirus GD01

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SARS-CoV Spike Protein ist gelabelt mit His tag.

Verwendungszweck: SARS-CoV GD01 Spike Trimer (R667A, KV968-969PP), His Tag (MALS verified)

Sequenz: Ser 14 - Pro 1195

Produktmerkmale: SARS-CoV GD01 Spike Trimer, His Tag (SPN-S52Ht) is expressed from human 293 cells (HEK293). It contains AA Ser 14 - Pro 1195 (Accession # AAP51227.1 (R667A, KV968-969PP).

Reinheit: >90 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Güteklasse: MALS verified

Anwendungsinformationen

Applikationshinweise: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 136.5 kDa. The protein migrates as kDa under reducing (R) condition due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))

Andere Bezeichnung: SARS-CoV Spike (SARS-CoV S Produkte)

Hintergrund: Synonyms:Spike,S protein,Spike glycoprotein,S glycoprotein,Description:It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Molekulargewicht: 136.5 kDa