CLMP Protein (His tag)
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- Target Alle CLMP Proteine anzeigen
- CLMP (CXADR-Like Membrane Protein (CLMP))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CLMP Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Mouse ASAM Protein (His Tag)(Active)
- Sequenz
- Met 1-Met 232
- Produktmerkmale
- A DNA sequence encoding the extracellular domain of mouse ASAM (Q8R373-1) (Met 1-Met 232) was expressed, with a polyhistidine tag at the C-terminus.
- Reinheit
- > 97 % as determined by SDS-PAGE
- Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by the ability of the immobilized protein to support the adhesion of the HUVEC human umbilical vein endothelial cell line. When 4 x 10E4 cells/well are added to mouse ASAM coated plates (30 μg/ml, 100 μl/well), approximately >40 % will adhere after one hour at 37 °C.
- Top Product
- Discover our top product CLMP Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CLMP (CXADR-Like Membrane Protein (CLMP))
- Andere Bezeichnung
- ASAM (CLMP Produkte)
- Synonyme
- ACAM Protein, ASAM Protein, CSBM Protein, CSBS Protein, Asam Protein, Ol16 Protein, 9030425E11Rik Protein, ASP5 Protein, AW557819 Protein, CXADR like membrane protein Protein, CXADR-like membrane protein Protein, CLMP Protein, Clmp Protein
- Hintergrund
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Background: Adipocyte-specific adhesion molecule (ASAM), also known as ACAM and CLMP, is a type I transmembrane protein and a member of the CTX (cortical thymocyte marker in Xenopus) family within the immunoglobulin superfamily. ASAM protein is highly expressed in the small intestine and placenta, and is found at intermediate levels in the heart, skeletal muscle, colon, spleen, kidney, and lung, and appears in low levels in the liver and peripheral blood leukocytes as well. ASAM is a transmembrane component of tight junctions in epithelial cells that can mediate cell aggregation and regulate transepithelial resistance across polarized epithelial cells. In addition, its expression is strongly correlated with white adipose tissue (WAT) mass of human and rodents with obesity.
Synonym: 9030425E11Rik,ACAM,ASP5,AW557819
- Molekulargewicht
- 25.6 kDa
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