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CD3D Protein (Fc Tag)

CD3D Spezies: Cynomolgus Wirt: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7320952
  • Target Alle CD3D Proteine anzeigen
    CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
    Protein-Typ
    Recombinant
    Spezies
    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Cynomolgus
    Quelle
    • 11
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses CD3D Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Cynomolgus CD3d/CD3 delta Protein (Fc Tag)
    Sequenz
    Phe22-Ala105
    Produktmerkmale
    Recombinant Cynomolgus CD3d is produced by our Mammalian expression system and the target gene encoding Phe22-Ala105 is expressed with a Fc tag at the C-terminus.
    Reinheit
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD3D Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
    Andere Bezeichnung
    CD3d/CD3 delta (CD3D Produkte)
    Synonyme
    CD3-DELTA Protein, T3D Protein, CD3 Protein, T3d Protein, CD3d molecule Protein, CD3 antigen, delta polypeptide Protein, CD3D Protein, Cd3d Protein
    Hintergrund

    Background: T-cell surface glycoprotein CD3 delta chain (CD3D) is a single-pass type I membrane protein. CD3D, together with CD3-gamma, CD3-epsilon and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. CD3 chains are present as CD3gammaepsilon, deltaepsilon, and zetazeta dimers in the receptor complex and play critical roles in the antigen receptor assembly, transport to the cell surface, and the receptor-mediated signal transduction. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs(ITAMs). CD3D contains 1 ITAM domain and has been shown to interact with CD8A.

    Synonym: T-cell surface glycoprotein CD3 delta chain, T-cell receptor T3 delta chain, CD3d, CD3D

    Molekulargewicht
    36.7 kDa
    UniProt
    Q95LI8
    Pathways
    T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events
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