SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (BA.5 - Omicron) (His tag)

Produktnummer ABIN7121589

Produktdetails

Target: SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

Protein-Typ: Recombinant

Proteineigenschaft: BA.5 - Omicron

Spezies: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SARS-CoV-2 Nucleocapsid Protein ist gelabelt mit His tag.

Verwendungszweck: SARS-CoV-2 Nucleocapsid protein, His Tag (BA.5/Omicron)

Sequenz: Met 1 - Ala 419

Spezifität: SARS-CoV-2 Nucleocapsid protein, His Tag (BA.5/Omicron) (P13L, ERS31-33del, E136D, R203K, G204R, S413R)

Produktmerkmale: SARS-CoV-2 Nucleocapsid protein, His Tag (BA.5/Omicron) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1(P13L, ERS31-33del, E136D, R203K, G204R, S413R). The mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.5; GISAID clade: GRA).

Anwendungsinformationen

Applikationshinweise: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.0 kDa.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from 0.22 μm filtered solution in PBS, 0.2M Arginine, pH7.4. Normally trehalose is added as protectant before lyophilization.

Lagerung: -20 °C

Informationen zur Lagerung: For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Antigendetails

Target: SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

Andere Bezeichnung: SARS-CoV-2 Nucleocapsid protein (SARS-CoV-2 N Produkte)

Synonyme: nucleocapsid phosphoprotein Protein, N Protein

Hintergrund: Synonym: Nucleocapsid protein, NP, Protein N
Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

Molekulargewicht: 47.0 kDa