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HHLA2 Protein (His tag)

MALS verified HHLA2 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN7121385
  • Target Alle HHLA2 Proteine anzeigen
    HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
    Protein-Typ
    Recombinant
    Spezies
    • 8
    • 2
    Cynomolgus
    Quelle
    • 8
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses HHLA2 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Cynomolgus B7-H7 / HHLA2 Protein, His Tag (MALS verified)
    Sequenz
    Ile 21 - Asn 345
    Produktmerkmale
    Cynomolgus B7-H7, His Tag (B77-C52H3) is expressed from human 293 cells (HEK293). It contains AA Ile 21 - Asn 345 (Accession # XP_005548285.1).
    Reinheit
    >95 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Güteklasse
    MALS verified
    Top Product
    Discover our top product HHLA2 Protein
  • Applikationshinweise
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39.2 kDa. The protein migrates as 60-70 kDa under reducing (R) condition due to glycosylation.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C
  • Target
    HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
    Andere Bezeichnung
    B7-H7 / HHLA2 (HHLA2 Produkte)
    Synonyme
    B7H7 Protein, HERV-H LTR-associating 2 Protein, HHLA2 Protein, hhla2 Protein
    Hintergrund
    Synonyms: B7-H7,HHLA2,B7 Homolog 7,
    Description: B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.
    Molekulargewicht
    39.2 kDa
    NCBI Accession
    XP_005548285
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