CLEC4C Protein (His tag)

Produktnummer ABIN7199198

Produktdetails

Target: CLEC4C (C-Type Lectin Domain Family 4, Member C (CLEC4C))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CLEC4C Protein ist gelabelt mit His tag.

Verwendungszweck: Human CLEC4C / BDCA2 Protein, His Tag (MALS verified)

Sequenz: Asn 45 - Ile 213

Produktmerkmale: Human CLEC4C, His Tag (CLC-H5245) is expressed from human 293 cells (HEK293). It contains AA Asn 45 - Ile 213 (Accession # Q8WTT0-1).

Reinheit: >90 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Güteklasse: MALS verified

Anwendungsinformationen

Applikationshinweise: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 26.6 kDa. The protein migrates as 33-40 kDa under reducing (R) condition due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: CLEC4C (C-Type Lectin Domain Family 4, Member C (CLEC4C))

Andere Bezeichnung: CLEC4C / BDCA2 (CLEC4C Produkte)

Synonyme: BDCA2 Protein, CD303 Protein, CLECSF11 Protein, CLECSF7 Protein, DLEC Protein, HECL Protein, PRO34150 Protein, Clec4c Protein, C-type lectin domain family 4 member C Protein, CLEC4C Protein, LOC100733227 Protein

Hintergrund: Synonyms: DLEC,CLEC4C,BDCA-2,CD303,CLECSF11,CLECSF7, HECL,
Description: CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.

Molekulargewicht: 26.6 kDa

NCBI Accession: NP_569708