KLRK1 Protein (AA 73-216) (Fc Tag,FITC)
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- Target Alle KLRK1 Proteine anzeigen
- KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 73-216
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses KLRK1 Protein ist gelabelt mit Fc Tag,FITC.
- Verwendungszweck
- FITC-Labeled Human NKG2D / CD314 Protein, Fc Tag
- Reinheit
- >90 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product KLRK1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Lagerung
- -20 °C
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- Target
- KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
- Andere Bezeichnung
- NKG2D (KLRK1 Produkte)
- Synonyme
- KLRK1 Protein, NKG2D Protein, CD314 Protein, D12S2489E Protein, KLR Protein, NKG2-D Protein, D6H12S2489E Protein, Nkg2d Protein, Nkrp2 Protein, killer cell lectin like receptor K1 Protein, killer cell lectin-like receptor subfamily K, member 1 Protein, NKG2D protein Protein, KLRK1 Protein, Klrk1 Protein, NKG2D Protein
- Hintergrund
- NKG2D is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors, also known as KLRK1, CD314, D12S2489E, KLR and killer cell lectin like receptor K1. NKG2D itself forms a homodimer whose ectodomains serve for ligand binding. NKG2D is a major recognition receptor for the detection and elimination of transformed and infected cells as its ligands are induced during cellular stress, either as a result of infection or genomic stress such as in cancer. In NK cells, NKG2D serves as an activating receptor, which itself is able to trigger cytotoxicity. The function of NKG2D on CD8+ T cells is to send co-stimulatory signals to activate them.
- Molekulargewicht
- 43.1 kDa
- Pathways
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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