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IL2RG Protein (AA 23-254) (His tag)

IL2RG Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN6992411
  • Target Alle IL2RG Proteine anzeigen
    IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 23-254
    Spezies
    • 17
    • 10
    • 3
    • 1
    • 1
    • 1
    Human
    Quelle
    • 13
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL2RG Protein ist gelabelt mit His tag.
    Verwendungszweck
    Human IL-2 R gamma / CD132 Protein, His Tag (MALS verified)
    Reinheit
    >95 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL2RG Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Lagerung
    -20 °C
  • Target
    IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
    Andere Bezeichnung
    IL-2 R gamma (IL2RG Produkte)
    Synonyme
    Ab2-183 Protein, Cd132 Protein, CD132 Protein, CIDX Protein, IL-2RG Protein, IMD4 Protein, P64 Protein, SCIDX Protein, SCIDX1 Protein, [g]c Protein, gamma(c) Protein, gc Protein, interleukin 2 receptor subunit gamma Protein, interleukin 2 receptor subunit gamma L homeolog Protein, interleukin 2 receptor, gamma chain Protein, IL2RG Protein, il2rg.L Protein, Il2rg Protein
    Hintergrund
    IL-2R is a heterotrimeric protein binds and responds to the cytokine IL-2. Three distinct chains of IL-2R, termed as α, β and γ, which are non-covalently associated are identified. The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ chain, along with the β subunit. The α chain of the IL-2R can bind to the β chain before receptor interaction with IL-2. The γ chain alone has a very weak affinity for IL-2, but after the ligand is bound to the α/β heterodimer, the γ chain becomes recruited to the complex to form a very stable macromolecular quaternary ligand/receptor complex. Interleukin-2 receptor subunit gamma (IL2RG), also known as cytokine receptor common subunit gamma, CD antigen CD132, gammaC, p64, which belongs to the type I cytokine receptor family or type 5 subfamily. IL2RG is located on the surface of immature blood-forming cells in bone marrow. Defects in IL2RG are the cause of severe combined immunodeficiency X-linked T-cell-negative/B-cell-positive/NK-cell-negative (XSCID).
    Molekulargewicht
    29.3 kDa
    Pathways
    JAK-STAT Signalweg, Growth Factor Binding
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