SARS-CoV-2 Spike Protein (B.1.617.1 - kappa) (rho-1D4 tag)

Produktnummer ABIN6976302

Produktdetails

Highlights:

• Recombinant trimeric S protein of the SARS-CoV-2 variant of concern B.1.617.
• Contains E154K, L452R, E484Q, D614G, and P681R mutations characteristic for the SARS-CoV-2 kappa variant (B.1.617.1).

Target: SARS-CoV-2 Spike

Protein-Typ: Recombinant

Proteineigenschaft: B.1.617.1 - kappa

Spezies: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Kappa

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SARS-CoV-2 Spike Protein ist gelabelt mit rho-1D4 tag.

Applikation: ELISA, Ligand Binding Assay (LBA)

Verwendungszweck: This is the spike protein of the mutant strain B.1.617, also commonly known as the "India" or "Kappa mutant".

Sequenz: 1286 amino acids (including Rho1D4 tag and linker)

Spezifität: Mutation that differ from "original" SPIKE protein: G142D, E154K, L452R, E484Q, D614G, P681R, Q1071H

Produktmerkmale: "SARS CoV-2 full-length Spike B.1.617 Mutation"
All viruses undergo fast mutations and adept quickly to the countermeasures that the immune systems creates against them. SARS-CoV-2 of the COVID-19 pandemic is no exception here. During the pandemic multiple mutant strains arose. To help the science combat these mutants we offer these mutant SPIKE proteins.
We offer the SPIKE protein of the mutants in full-length and active in their native trimeric form, stabilized with the LMNG detergent.

Reinheit: > 98% as determined by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Further modifications:
- furin cleavage site "682-RRAR|SV-687" mutated to "682-GSAG|PP-687"
- C-terminal Rho1D4 tag fused with spacer "GSSG" to protein sequence
Size: 1286 amino acids (including Rho1D4 tag and linker)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 20 mM Hepes pH 7.5, 150 mM NaCl, 0.001 % LMNG

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Avoid freeze-thaw cycles

Antigendetails

Target: SARS-CoV-2 Spike

Andere Bezeichnung: SARS2 Spike glycoprotein (SARS-CoV-2 Spike Produkte)

Synonyme: E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein

Substanzklasse: Viral Protein

Hintergrund: All viruses undergo fast mutations and adapt quickly to the countermeasures that the immune systems creates. SARS-CoV-2 of the COVID-19 pandemic is no exception to this. During the pandemic multiple mutant strains arose.

Molekulargewicht: 142190.43 Da

UniProt: P0DTC2