SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (D3L, G204R, R203K, S235F) (His tag)

Produktnummer ABIN6971314

Produktdetails

Target: SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

Protein-Typ: Recombinant

Proteineigenschaft: D3L, G204R, R203K, S235F

Spezies: SARS Coronavirus-2 (SARS-CoV-2)

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SARS-CoV-2 Nucleocapsid Protein ist gelabelt mit His tag.

Verwendungszweck: SARS-CoV-2 Nucleocapsid protein (D3L, S235F), His Tag

Sequenz: AA 1-419

Produktmerkmale: SARS-CoV-2 Nucleocapsid protein (D3L, S235F), His Tag is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (D3L, S235F) (Accession # QHO62115.1(D3L, S235F). D3L/ S235F were identified in the SARS-CoV-2 variant (known as 20B/501Y.V1, VOC 202012/01, or B.1.1.7 lineage) which emerged in the United Kindom.

Reinheit: >90 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Haltbarkeit: 12 months

Antigendetails

Target: SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

Andere Bezeichnung: SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N Produkte)

Synonyme: nucleocapsid phosphoprotein Protein, N Protein

Substanzklasse: Viral Protein

Hintergrund: Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology, 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

Molekulargewicht: 47.4 kDa