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Zona Pellucida Glycoprotein 3 Protein (ZP3) (Fc Tag)

ZP3 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN6964410
  • Target Alle Zona Pellucida Glycoprotein 3 (ZP3) Proteine anzeigen
    Zona Pellucida Glycoprotein 3 (ZP3)
    Protein-Typ
    Recombinant
    Spezies
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 6
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Zona Pellucida Glycoprotein 3 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant human ZP3 protein with C-terminal human Fc tag
    Spezifität
    ZP3 (Gln23-Ser386) hFc (Glu99-Ala330)
    Produktmerkmale
    Extracellular Domain Protein
    Aufreinigung
    affinity purification
    Reinheit
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product ZP3 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Konservierungsmittel
    Without preservative
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    Zona Pellucida Glycoprotein 3 (ZP3)
    Andere Bezeichnung
    ZP3 (ZP3 Produkte)
    Synonyme
    ZP3A Protein, ZP3B Protein, ZPC Protein, Zp-3 Protein, zp3.2 Protein, Zp-3B Protein, zona pellucida glycoprotein 3 Protein, zona pellucida sperm-binding protein 3 Protein, ZP3 Protein, zp3 Protein, Zp3 Protein
    Hintergrund
    Synonymes: OOMD3, Zp-3, ZP3A, ZP3B, ZPC
    Description: The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a C-terminal consensus furin cleavage site, and a transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus
    Molekulargewicht
    predicted molecular mass of 66.6 kDa after removal of the signal peptide. The apparent molecular mass of ZP3-hFc is 70-100 kDa due to glycosylation.
    Gen-ID
    7784
    UniProt
    P21754
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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