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CCR1 Protein (Fc Tag)

CCR1 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN6964237
  • Target Alle CCR1 Proteine anzeigen
    CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))
    Protein-Typ
    Recombinant
    Spezies
    • 6
    • 3
    • 1
    Human
    Quelle
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CCR1 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant human CCR1 protein with C-terminal human Fc tag
    Spezifität
    CCR1 (Met1-Ala34) hFc (Glu99-Ala330)
    Produktmerkmale
    Extracellular Domain Protein
    Aufreinigung
    affinity purification
    Reinheit
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CCR1 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Konservierungsmittel
    Without preservative
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))
    Andere Bezeichnung
    CCR1 (CCR1 Produkte)
    Synonyme
    CD191 Protein, CKR-1 Protein, CKR1 Protein, CMKBR1 Protein, HM145 Protein, MIP1aR Protein, SCYAR1 Protein, Cmkbr1 Protein, Mip-1a-R Protein, C-C motif chemokine receptor 1 Protein, chemokine (C-C motif) receptor 1 Protein, CCR1 Protein, Ccr1 Protein
    Hintergrund
    Synonymes: CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
    Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
    Molekulargewicht
    predicted molecular mass of 30.0 kDa after removal of the signal peptide. The apparent molecular mass of CCR1-hFc is 35-55 kDa due to glycosylation.
    UniProt
    P32246
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