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BAI1 Protein (Fc Tag)

BAI1 Spezies: Human Wirt: HEK-293 Cells Recombinant
Produktnummer ABIN6964229
  • Target Alle BAI1 Proteine anzeigen
    BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
    Protein-Typ
    Recombinant
    Spezies
    • 4
    • 3
    Human
    Quelle
    • 6
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses BAI1 Protein ist gelabelt mit Fc Tag.
    Sequenz
    BAI1(Ala31-Ser948)+6xHis tag
    Produktmerkmale
    Tagged Protein: C-Human Fc tag
    Aufreinigung
    affinity purification
    Top Product
    Discover our top product BAI1 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Konservierungsmittel
    Without preservative
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    Haltbarkeit
    12 months
  • Target
    BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
    Andere Bezeichnung
    BAI1 (BAI1 Produkte)
    Synonyme
    BAI1 Protein, GDAIF Protein, B830018M07Rik Protein, R75078 Protein, mKIAA4089 Protein, brain-specific angiogenesis inhibitor 1 Protein, adhesion G protein-coupled receptor B1 Protein, BAI1 Protein, ADGRB1 Protein, LOC100228084 Protein, Adgrb1 Protein
    Hintergrund
    Synonymes: BAI1, GDAIF
    Description: Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008]
    Molekulargewicht
    101.64 kDa
    UniProt
    O14514
    Pathways
    p53 Signalweg
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