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CRLF2 Protein (Fc Tag)

CRLF2 Spezies: Human Wirt: HEK-293 Cells Recombinant
Produktnummer ABIN6964184
  • Target Alle CRLF2 Proteine anzeigen
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    Protein-Typ
    Recombinant
    Spezies
    • 12
    • 8
    • 1
    • 1
    Human
    Quelle
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CRLF2 Protein ist gelabelt mit Fc Tag.
    Sequenz
    CRLF2(Gln23-Lys231)+hFc(Glu99-Ala330)
    Produktmerkmale
    Tagged Protein: C-Human Fc tag
    Aufreinigung
    affinity purification
    Top Product
    Discover our top product CRLF2 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Konservierungsmittel
    Without preservative
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    Haltbarkeit
    12 months
  • Target
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    Andere Bezeichnung
    CRLF2 (CRLF2 Produkte)
    Synonyme
    CRLF2 Protein, CRL2 Protein, CRLF2Y Protein, TSLPR Protein, CRLM2 Protein, Ly114 Protein, Tpte2 Protein, Tslpr Protein, Crl2 Protein, cytokine receptor like factor 2 Protein, cytokine receptor-like factor 2 Protein, CRLF2 Protein, Crlf2 Protein
    Hintergrund
    Synonymes: CRL2, CRLF2Y, TSLPR
    Description: This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.
    Molekulargewicht
    48.51 kDa
    UniProt
    Q9HC73
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