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CCR7 Protein (Fc Tag)

CCR7 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN6964145
  • Target Alle CCR7 Proteine anzeigen
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 3
    • 1
    Human
    Quelle
    • 3
    • 3
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CCR7 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human CCR7 with C-terminal human Fc tag
    Spezifität
    CCR7 (Glu25-Trp59) hFc (Glu99-Ala330)
    Produktmerkmale
    Extracellular Domain Protein
    Aufreinigung
    affinity purification
    Reinheit
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CCR7 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Konservierungsmittel
    Without preservative
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    Andere Bezeichnung
    CCR7 (CCR7 Produkte)
    Synonyme
    zgc:165629 Protein, ccr7-a Protein, CD197 Protein, Cdw197 Protein, Cmkbr7 Protein, EBI1 Protein, Ebi1h Protein, BLR2 Protein, CDw197 Protein, CMKBR7 Protein, chemokine (C-C motif) receptor 7 Protein, C-C motif chemokine receptor 7 Protein, C-C motif chemokine receptor 7 L homeolog Protein, ccr7 Protein, CCR7 Protein, ccr7.L Protein, Ccr7 Protein
    Hintergrund
    Synonymes: BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1
    Description: The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.
    Molekulargewicht
    predicted molecular mass of 30.2 kDa after removal of the signal peptide. The apparent molecular mass of CCR7-hFc is 35-55 kDa due to glycosylation.
    UniProt
    P32248
    Pathways
    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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