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IL-6 Protein (mFc-His Tag)

IL6 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA, FACS
Produktnummer ABIN6961105
  • Target Alle IL-6 (IL6) Proteine anzeigen
    IL-6 (IL6) (Interleukin 6 (IL6))
    Protein-Typ
    Recombinant
    Spezies
    • 32
    • 18
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 52
    • 24
    • 20
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL-6 Protein ist gelabelt mit mFc-His Tag.
    Applikation
    ELISA, Flow Cytometry (FACS)
    Verwendungszweck
    Recombinant human IL6 protein with C-terminal mouse Fc and 6xHis tag
    Spezifität
    IL6 (Val30-Met212) mFc (Pro99-Lys330) 6xHis tag
    Produktmerkmale
    Extracellular Domain Protein
    Aufreinigung
    affinity purification
    Reinheit
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Konservierungsmittel
    Without preservative
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    IL-6 (IL6) (Interleukin 6 (IL6))
    Andere Bezeichnung
    IL6 (IL6 Produkte)
    Synonyme
    BSF2 Protein, HGF Protein, HSF Protein, IFNB2 Protein, IL-6 Protein, Il-6 Protein, ILg6 Protein, Ifnb2 Protein, il6 Protein, CHIL-6 Protein, interleukin 6 Protein, interleukin-6 Protein, IL6 Protein, Il6 Protein, il-6 Protein, IL-6 Protein
    Hintergrund
    Synonymes: IL6, Interleukin-6, BSF2, HSF, IFNB2
    Description: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
    Molekulargewicht
    predicted molecular mass of 47.9 kDa after removal of the signal peptide.
    Gen-ID
    3569
    UniProt
    P05231
    Pathways
    TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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