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SARS-Coronavirus Nonstructural Protein 8 (SARS-CoV NSP8) protein (His tag)

SARS-CoV NSP8 Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE. SDS
Produktnummer ABIN6952706
  • Target Alle SARS-Coronavirus Nonstructural Protein 8 (SARS-CoV NSP8) Produkte
    SARS-Coronavirus Nonstructural Protein 8 (SARS-CoV NSP8)
    Protein-Typ
    Recombinant
    Spezies
    SARS Coronavirus-2 (SARS-CoV-2)
    Quelle
    • 11
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    His tag
    Applikation
    SDS-PAGE (SDS)
    Verwendungszweck
    SARS-CoV-2 (COVID-19) NSP8 Protein, His Tag
    Sequenz
    AA 1-198
    Produktmerkmale
    SARS-CoV-2 NSP8, His Tag (NS8-C5149) is expressed from E.coli cells. It contains AA Ala 1 - Gln 198 (Accession # YP_009725304.1).Predicted N-terminus: Met
    This protein carries a polyhistidine tag at the N-terminus.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    20 mM Tris, 250 mM NaCl, pH 8.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    The product MUST be stored at -70°C or lower upon receipt
    -70°C for 3 months under sterile conditions.
  • Target
    SARS-Coronavirus Nonstructural Protein 8 (SARS-CoV NSP8)
    Andere Bezeichnung
    NSP8 (SARS-CoV NSP8 Produkte)
    Synonyme
    pp1a Protein, pp1ab Protein, orf1ab polyprotein (pp1ab) Protein, orf1ab Protein
    Substanzklasse
    Viral Protein
    Hintergrund
    NSP8, forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. By investigating the entire proteome of SARS-CoV-2, six proteins, including the S protein and five non-structural proteins (nsp3, 3CL-pro, and nsp8-10) were predicted to be adhesins, which are crucial to the viral adhering and host invasion. The S, nsp3, and nsp8 proteins were also predicted by Vaxign-ML to induce high protective antigenicity.
    Molekulargewicht
    23.9 kDa
    NCBI Accession
    YP_009725304
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