VHL Protein (AA 1-172) (GST tag)

Produktnummer ABIN1325000

Produktdetails

Target: VHL (Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-172

Spezies: Human

Quelle: Wheat germ

Aufreinigungstag / Konjugat: Dieses VHL Protein ist gelabelt mit GST tag.

Applikation: Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)

Verwendungszweck: VHL (Human) Recombinant Protein (P01)

Sequenz: MPRRAENWDE AEVGAEEAGV EEYGPEEDGG EESGAEESGP EESGPEELGA EEEMEAGRPR PVLRSVNSRE PSQVIFCNRS PRVVLPVWLN FDGEPQPYPT LPPGTGRRIH SYRVYTLKER CLQVVRSLVK PENYRRLDIV RSLYEDLEDH PNVQKDLERL TQERIAHQRM GD

Produktmerkmale: Human VHL full-length ORF ( ENSP00000344757, 1 a.a. - 172 a.a.) recombinant protein with GST-tag at N-terminal.

Aufreinigung: in vitro wheat germ expression system

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -80 °C

Informationen zur Lagerung: Best use within three months from the date of receipt of this protein.

Referenzen

Kim, Lee, Jang, Yi, Kim, Han, Lee, Tong, Vincelette, Gao, Yin, Evans, Choi, Qin, Liu, Zhang, Deng, Jen, Zhang, Wang, Lou: "WSB1 promotes tumor metastasis by inducing pVHL degradation." in: Genes & development, Vol. 29, Issue 21, pp. 2244-57, (2015) (PubMed).

Antigendetails

Target: VHL (Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL))

Andere Bezeichnung: VHL (VHL Produkte)

Synonyme: HRCA1 Protein, RCA1 Protein, VHL1 Protein, pVHL Protein, BcDNA:RH61560 Protein, CG13221 Protein, DVhl Protein, Dmel\\CG13221 Protein, Dvhl Protein, VHL Protein, d-VHL Protein, d-vhl Protein, dVHL Protein, dmVHL Protein, vhl Protein, rca1 Protein, vhl1 Protein, hrca1 Protein, zgc:158722 Protein, Vhlh Protein, von Hippel-Lindau tumor suppressor Protein, von Hippel-Lindau Protein, von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase Protein, von Hippel-Lindau disease tumor suppressor Protein, VHL Protein, Vhl Protein, vhl Protein, CpipJ_CPIJ009992 Protein

Hintergrund: Full Gene Name: von Hippel-Lindau tumor suppressor
Synonyms: HRCA1,RCA1,VHL1

Gen-ID: 7428

Pathways: Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Ubiquitin Proteasome Pathway