VOPP1 Protein (AA 82-172) (His tag)

Produktnummer ABIN7279458

Produktdetails

Target: VOPP1 (Vesicular, Overexpressed in Cancer, Prosurvival Protein 1 (VOPP1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 82-172

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses VOPP1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: VOPP1, 82-172aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.2M NaCl

Lagerung: 4 °C

Antigendetails

Target: VOPP1 (Vesicular, Overexpressed in Cancer, Prosurvival Protein 1 (VOPP1))

Andere Bezeichnung: VOPP1 (VOPP1 Produkte)

Synonyme: Ecop Protein, RGD1306494 Protein, ecop Protein, gasp Protein, ECOP Protein, GASP Protein, AW146242 Protein, vesicular, overexpressed in cancer, prosurvival protein 1 Protein, vesicular, overexpressed in cancer, prosurvival protein 1 S homeolog Protein, si:dkey-24c2.9 Protein, EGFR-coamplified and overexpressed protein Protein, Vopp1 Protein, vopp1.S Protein, vopp1 Protein, si:dkey-24c2.9 Protein, VOPP1 Protein, ecop Protein

Hintergrund: Vesicular, overexpressed in cancer, prosurvival protein 1(VOPP1), also known as Glioblastoma-amplified secreted protein (GASP), has been previously shown to be over-expressed in human glioblastoma multiforme and squamous cell carcinoma. VOPP1 is a key regulator of NF-kappaB signaling, and that high-level, amplification-mediated VOPP1 expression, such as that occurring in tumors with amplified EGFR, could contribute to resistance to apoptosis. Recombinant human VOPP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Vesicular, overexpressed in cancer, prosurvival protein 1, ECOP, GASP. NCBI no.: NP_110423

Molekulargewicht: 12 kDa (112aa), confirmed by MALDI-TOF