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CTDSP1 Protein (AA 1-260) (His tag)

CTDSP1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN667902
  • Target Alle CTDSP1 Proteine anzeigen
    CTDSP1 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-260
    Spezies
    • 5
    • 1
    Human
    Quelle
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses CTDSP1 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    CTDSP1, 1-260aa, Human, His tag, E.coli
    Reinheit
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product CTDSP1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl
    Lagerung
    4 °C
  • Target
    CTDSP1 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1))
    Andere Bezeichnung
    CTDSP1 (CTDSP1 Produkte)
    Synonyme
    CTDSP1 Protein, NIF3 Protein, NLI-IF Protein, NLIIF Protein, SCP1 Protein, fj83f12 Protein, im:7141428 Protein, wu:fj83f12 Protein, zgc:113169 Protein, GIP Protein, Nif3 Protein, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 Protein, CTD small phosphatase 1 Protein, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 Protein, CTDSP1 Protein, Ctdsp1 Protein, ctdsp1 Protein, HCAG_04820 Protein, CTRG_06220 Protein
    Hintergrund
    Carboxy-terminal domain, RNA polymerase II, polypeptide A phosphatase 1, also known as CTDSP1, is a class 2C phosphatase with activity dependent on the conserved DxD motif. CTDSP1 preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Also it negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recombinant human CTDSP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Carboxy-terminal domain, RNA polymerase II, polypeptide A phosphatase 1, NLIIF, SCP1, NIF3. NCBI no.: NP_872580
    Molekulargewicht
    31.2 kDa (280aa), confirmed by MALDI-TOF
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