EEF1D Protein (AA 1-281) (His tag)

Produktnummer ABIN667885

Produktdetails

Target: EEF1D (Eukaryotic Translation Elongation Factor 1 delta (Guanine Nucleotide Exchange Protein) (EEF1D))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-281

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses EEF1D Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: EEF1D, 1-281aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: EEF1D (Eukaryotic Translation Elongation Factor 1 delta (Guanine Nucleotide Exchange Protein) (EEF1D))

Andere Bezeichnung: EEF1D (EEF1D Produkte)

Synonyme: EF-1D Protein, EF1D Protein, FP1047 Protein, EEF1D Protein, 1700026P12Rik Protein, 5730529A16Rik Protein, AL023999 Protein, delta Protein, dyak_GLEANR_2691 Protein, DyakGE18908 Protein, GE18908 Protein, eEF1delta Protein, eef1d Protein, im:7233939 Protein, si:dkey-235d18.4 Protein, wu:fa14f09 Protein, zgc:114052 Protein, eukaryotic translation elongation factor 1 delta Protein, elongation factor 1 delta Protein, eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) S homeolog Protein, eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) Protein, eukaryotic translation Elongation Factor 1 delta Protein, eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein) Protein, elongation factor-1 delta Protein, EEF1D Protein, RABEF1D Protein, eef1d.S Protein, Eef1d Protein, Dyak\eEF1delta Protein, LOC100304800 Protein, eef1db Protein, eef1d Protein

Hintergrund: Eukaryotic translation elongation factor 1 delta, also known as EEF1D, is a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit functions as guanine nucleotide exchange factor. It is reported that this subunit interacts with HIV-1 Tat, and thus it represses the translation of host-cell, but not HIV-1, mRNAs. Overexpression of EEF1D is associated with oesophageal carcinoma and may adversely affect the outcome of medulloblastomas. Recombinant human EEF1D protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Eukaryotic translation elongation factor 1 delta, EF-1D, EF1D. NCBI no.: NP_001951

Molekulargewicht: 33.2 kDa (301aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)