TXNL1 Protein (AA 1-289) (His tag)
Kurzübersicht für TXNL1 Protein (AA 1-289) (His tag) (ABIN667868)
Target
Alle TXNL1 Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- AA 1-289
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Aufreinigungstag / Konjugat
- Dieses TXNL1 Protein ist gelabelt mit His tag.
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Sequenz
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MVGVKPVGSD PDFQPELSGA GSRLAVVKFT MRGCGPCLRI APAFSSMSNK YPQAVFLEVD VHQCQGTAAT NNISATPTFL FFRNKVRIDQ YQGADAVGLE EKIKQHLEND PGSNEDTDIP KGYMDLMPFI NKAGCECLNE SDEHGFDNCL RKDTTFLESD CDEQLLITVA FNQPVKLYSM KFQGPDNGQG PKYVKIFINL PRSMDFEEAE RSEPTQALEL TEDDIKEDGI VPLRYVKFQN VNSVTIFVQS NQGEEETTRI SYFTFIGTPV QATNMNDFKR VVGKKGESH -
Produktmerkmale
- TXNL1, 1-289aa, Human, His tag, E.coli
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Aufreinigung
- > 95% by SDS-PAGE
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 5 mM DTT, 20 % glycerol
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- TXNL1 (Thioredoxin-Like 1 (TXNL1))
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Andere Bezeichnung
- TXNL1
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Hintergrund
- TXNL1, also known as TRP32, TXL or TXL-1, is a cytoplasmic protein that participates in endocytotic signaling pathways and acts as a redox sensor. Expressed throughout the body, TXNL1 functions to couple oxidative stress to endocytosis, thereby regulating the GDI. Additionally, overexpression of TXNL1 inhibits cell proliferation by predisposing the cell to G0/G1 arrest, suggesting that TXNL1 also functions as a transcriptional repressor. Recombinant human TXNL1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
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Molekulargewicht
- 34.4 kDa (309aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_004777
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Pathways
- Cell RedoxHomeostasis
Target
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